Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 7/20 | 0.36 |
| ▸ | ADAMTS5 | Q9UNA0 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6267381 | 0.88 | ADAMTS5 (0.41) | NPC1RAB9AADAMTS5ALDH1A1 | |
| SCHEMBL6272309 | 0.88 | ADAMTS5 (0.38) | NPC1RAB9ANPY5RCYP19A1ADAMTS5 | |
| SCHEMBL6268735 | 0.83 | GCGR (0.39) | RAB9ACYP19A1ADAMTS5ALDH1A1 | |
| SCHEMBL6260436 | 0.79 | MECP2 (0.47) | NPC1RAB9AADAMTS5ALDH1A1 | |
| SCHEMBL6271575 | 0.75 | ADAMTS5 (0.35) | CYP19A1ADAMTS5ALDH1A1 | |
| SCHEMBL6260546 | 0.73 | ADAMTS5 (0.36) | ADAMTS5ALDH1A1 | |
| SCHEMBL6278562 | 0.72 | ADAMTS5 (0.35) | NPC1RAB9AADAMTS5ALDH1A1 | |
| SCHEMBL6262704 | 0.72 | ADAMTS5 (0.49) | ADAMTS5ALDH1A1 | |
| SCHEMBL6274589 | 0.70 | ADAMTS5 (0.36) | ADAMTS5ALDH1A1 | |
| SCHEMBL6274201 | 0.69 | ADAMTS5 (0.37) | ADAMTS5ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005092304-A2 | ANTIFUNGAL AGENTS | F2G LTD (GB) | 2005-10-06 | — | — | WO | claimed |