Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TK1 | P04183 | 3/20 | 0.66 |
| ▸ | LMNA | P02545 | 2/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.66 |
| ▸ | TK2 | O00142 | 1/20 | 0.64 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.62 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.60 |
| ▸ | TSHR | P16473 | 1/20 | 0.60 |
| ▸ | BLM | P54132 | 1/20 | 0.60 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6272366 | 1.00 | TK1 (0.66) | TK1LMNASMN1; SMN2TK2ALOX12 | |
| SCHEMBL439723 | 1.00 | TK1 (0.66) | TK1LMNASMN1; SMN2TK2ALOX12 | |
| SCHEMBL439722 | 1.00 | TK1 (0.66) | TK1LMNASMN1; SMN2TK2ALOX12 | |
| SCHEMBL20750697 | 1.00 | TK1 (0.66) | TK1LMNASMN1; SMN2TK2ALOX12 | |
| Water SCHEMBL9633588 | 0.99 | TK1 (0.65) | TK1LMNASMN1; SMN2TK2ALOX12 | |
| Water SCHEMBL9633592 | 0.99 | TK1 (0.65) | TK1LMNASMN1; SMN2TK2ALOX12 | |
| SCHEMBL7707472 | 0.92 | TK1 (0.58) | TK1LMNASMN1; SMN2TK2ALOX12 | |
| SCHEMBL15740099 | 0.89 | TK1 (0.64) | TK1LMNASMN1; SMN2TK2ALOX12 | |
| SCHEMBL4263793 | 0.89 | TK1 (0.64) | TK1LMNASMN1; SMN2TK2ALOX12 | |
| SCHEMBL12047413 | 0.89 | TK1 (0.65) | TK1LMNASMN1; SMN2TK2ALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1600451-A2 | Synthesis of 2'-deoxy-l-nucleosides | Pharmasset Limited (US) | 2005-11-30 | — | — | EP | disclosed |
| EP-1600452-A2 | Synthesis of 2'-deoxy-L-nucleosides | Pharmasset Limited (US) | 2005-11-30 | — | — | EP | disclosed |
| US-20050090660-A1 | 2'-deoxy-L-nucleosides | PHARMASSET, INC. | 2005-04-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050090660-A1 | 2'-deoxy-L-nucleosides | CCNH, ADAR, NSUN2 | TK1 661/4885LMNA 845/4885SMN1; SMN2 2345/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.