SCHEMBL439722

SCHEMBL439722

CC#Cc1cn([C@H]2C[C@H](O)[C@@H](CO)O2)c(=O)[nH]c1=O

nearest known ligand 0.66

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TK1 P04183 3/20 0.66
LMNA P02545 2/20 0.66
SMN1; SMN2 Q16637 2/20 0.66
TK2 O00142 1/20 0.64
ALOX12 P18054 1/20 0.62
ADRA1A P35348 1/20 0.62
CYP1A2 P05177 1/20 0.60
CYP3A4 P08684 1/20 0.60
TSHR P16473 1/20 0.60
BLM P54132 1/20 0.60
PMP22 Q01453 1/20 0.60
NPSR1 Q6W5P4 1/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6272366 1.00 TK1 (0.66) TK1LMNASMN1; SMN2TK2ALOX12
SCHEMBL6272364 1.00 TK1 (0.66) TK1LMNASMN1; SMN2TK2ALOX12
SCHEMBL439723 1.00 TK1 (0.66) TK1LMNASMN1; SMN2TK2ALOX12
SCHEMBL20750697 1.00 TK1 (0.66) TK1LMNASMN1; SMN2TK2ALOX12
Water SCHEMBL9633588 0.99 TK1 (0.65) TK1LMNASMN1; SMN2TK2ALOX12
Water SCHEMBL9633592 0.99 TK1 (0.65) TK1LMNASMN1; SMN2TK2ALOX12
SCHEMBL7707472 0.92 TK1 (0.58) TK1LMNASMN1; SMN2TK2ALOX12
SCHEMBL15740099 0.89 TK1 (0.64) TK1LMNASMN1; SMN2TK2ALOX12
SCHEMBL4263793 0.89 TK1 (0.64) TK1LMNASMN1; SMN2TK2ALOX12
SCHEMBL12047413 0.89 TK1 (0.65) TK1LMNASMN1; SMN2TK2ALOX12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1202 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250263678-A1 COMPOSITIONS AND METHODS FOR DELIVERY OF RNA REJUVENATION TECHNOLOGIES, INC. (US) 2025-08-21 US claimed
WO-2025024123-A1 NOVEL CITICOLINE DERIVATIVES THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2025-01-30 WO claimed
EP-4271389-A1 COMPOSITIONS AND METHODS FOR DELIVERY OF RNA Rejuvenation Technologies Inc. (US) 2023-11-08 EP claimed
CN-116916936-A Compositions and methods for delivering RNA 再生技术有限责任公司 2023-10-20 CN claimed
CN-103687961-B Methods and compositions for isothermal whole genome amplification 赛雷纳(中国)医疗科技有限公司 2022-11-22 CN claimed
WO-2022147039-A1 COMPOSITIONS AND METHODS FOR DELIVERY OF RNA REJUVENATION TECHNOLOGIES INC. (US) 2022-07-07 WO claimed
CN-111334562-A Nucleic acid amplification method and kit containing modified primer 合肥铼科生物科技有限公司 2020-06-26 CN claimed
EP-2705166-A1 METHODS AND COMPOSITIONS FOR ISOTHERMAL WHOLE GENOME AMPLIFICATION Celula Inc. (US) 2014-03-12 EP claimed
WO-2012154614-A1 METHODS AND COMPOSITIONS FOR ISOTHERMAL WHOLE GENOME AMPLIFICATION CELULA, INC. (US) 2012-11-15 WO claimed
US-20100292135-A1 INHIBITORS OF RecA ACTIVITIES FOR CONTROL OF ANTIBIOTIC-RESISTANT BACTERIAL PATHOGENS NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2010-11-18 US claimed
WO-1999027086-A1 CHIMERIC ANTISENSE OLIGONUCLEOTIDES AGAINST TNF-ALPHA AND THEIR USES BRAX GROUP LIMITED (GB) 1999-06-03 WO claimed
EP-0857208-A2 CHIMAERIC OLIGONUCLEOTIDES AND USES THEREOF IN THE IDENTIFICATION OF ANTISENSE BINDING SITES Brax Genomics Limited (GB) 1998-08-12 EP claimed
US-5763208-A Oligonucleotides and their analogs capable of passive cell membrane permeation GILEAD SCIENCES, INC. (US) 1998-06-09 US claimed
WO-1998004575-A2 LIPOPHILIC OLIGONUCLEOTIDE ANALOGS GILEAD SCIENCES, INC. (US) 1998-02-05 WO claimed
WO-1997049833-A1 METHOD FOR PRODUCING HYBRIDISATION COMPLEXES WHOSE STABILITY IS SUBSTANTIALLY INDEPENDENT OF THE BASE COMPOSITION OF TWO HYBRIDISED NUCLEIC ACID MOLECULES APPLIGENE-ONCOR S.A. (FR) 1997-12-31 WO claimed
US-5633360-A CONTAINS AT LEAST TWO NUCLEOSIDE RESIDUES AND INTERNUCLEOTIDE LINKAGES GILEAD SCIENCES, INC. (US) 1997-05-27 US claimed
WO-1997010332-A2 CHIMAERIC OLIGONUCLEOTIDES AND USES THEREOF IN THE IDENTIFICATION OF ANTISENSE BINDING SITES BRAX GENOMICS LIMITED (GB) 1997-03-20 WO claimed
EP-0573479-A1 CHIMERIC TAR ENZYME CONSTRUCTION FOR HIV THERAPY THE WELLCOME FOUNDATION LIMITED (GB) 1993-12-15 EP claimed
WO-1992015693-A1 CHIMERIC TAR ENZYME CONSTRUCTION FOR HIV THERAPY THE WELLCOME FOUNDATION LIMITED (GB) 1992-09-17 WO claimed
EP-0272065-A2 Antiviral compounds THE WELLCOME FOUNDATION LIMITED (GB) 1988-06-22 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250263678-A1 COMPOSITIONS AND METHODS FOR DELIVERY OF RNA RNASE1, POLRMT, TERT TK1 156/4885LMNA 233/4885SMN1; SMN2 58/4885
US-20100292135-A1 INHIBITORS OF RecA ACTIVITIES FOR CONTROL OF ANTIBIOTIC-RESISTANT BACTERIAL PATHOGENS RECQL, DNA2, WRN TK1 656/4885LMNA 305/4885SMN1; SMN2 3098/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.