Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 1/20 | 0.61 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.56 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | CRHBP | P24387 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.50 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.50 |
| ▸ | BCHE | P06276 | 5/20 | 0.49 |
| ▸ | ACHE | P22303 | 5/20 | 0.49 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.49 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.49 |
| ▸ | CDK4 | P11802 | 1/20 | 0.48 |
| ▸ | CCND1 | P24385 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23925502 | 0.87 | AOC3 (0.61) | AOC3MTNR1AMTNR1BMEN1CRHBP | |
| SCHEMBL6272334 | 0.84 | AOC3 (0.61) | AOC3MTNR1AMTNR1BMEN1CRHBP | |
| SCHEMBL8285804 | 0.82 | MTNR1A (0.45) | MTNR1AMTNR1B | |
| SCHEMBL2937482 | 0.79 | AOC3 (0.73) | AOC3TAAR1BCHECHRM2SIGMAR1 | |
| Hydrochloric Acid SCHEMBL8509376 | 0.78 | AOC3 (0.71) | AOC3TAAR1BCHECHRM2SIGMAR1 | |
| SCHEMBL31719788 | 0.77 | TAAR1 (0.62) | MTNR1AMTNR1BKMT2ATAAR1CDK4 | |
| SCHEMBL7568527 | 0.77 | TSPO (0.61) | — | |
| SCHEMBL30365164 | 0.76 | MTNR1A (0.63) | MTNR1AMTNR1BKMT2ATAAR1SIGMAR1 | |
| SCHEMBL266525 | 0.76 | MTNR1A (0.63) | MTNR1AMTNR1BKMT2ATAAR1SIGMAR1 | |
| SCHEMBL19399106 | 0.75 | NPSR1 (0.44) | MTNR1AMTNR1BMEN1CRHBPKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1608617-A1 | MUSCARINIC AGONISTS | ELI LILLY AND COMPANY (US) | 2005-12-28 | — | — | EP | disclosed |
| WO-2004094363-A1 | MUSCARINIC AGONISTS | ELI LILLY AND COMPANY (US) | 2004-11-04 | — | — | WO | disclosed |