Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 1/20 | 0.45 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | GHSR | Q92847 | 2/20 | 0.44 |
| ▸ | HRH1 | P35367 | 2/20 | 0.43 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | DRD1 | P21728 | 1/20 | 0.41 |
| ▸ | DRD4 | P21917 | 1/20 | 0.41 |
| ▸ | DRD5 | P21918 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12634482 | 0.83 | DRD2 (0.54) | KDM4EALDH1A1SMN1; SMN2HRH1DRD2 | |
| SCHEMBL6272891 | 0.82 | AOC3 (0.61) | MTNR1AMTNR1B | |
| SCHEMBL7650232 | 0.78 | GHSR (0.41) | KDM4EALDH1A1GHSRHRH1 | |
| SCHEMBL12635016 | 0.77 | BCHE (0.41) | KDM4EALDH1A1SMN1; SMN2GHSRHRH1 | |
| SCHEMBL10335287 | 0.76 | ALDH1A1 (0.48) | ALDH1A1SMN1; SMN2DRD2 | |
| SCHEMBL7648747 | 0.76 | GHSR (0.65) | MTNR1AMTNR1BGHSR | |
| SCHEMBL8284011 | 0.75 | MTNR1A (0.68) | MTNR1AMTNR1BKDM4EALDH1A1 | |
| SCHEMBL8507880 | 0.75 | GHSR (0.49) | KDM4EALDH1A1GHSR | |
| SCHEMBL73790 | 0.75 | PPARD (0.54) | ALDH1A1 | |
| SCHEMBL12634753 | 0.75 | GHSR (0.41) | KDM4EALDH1A1SMN1; SMN2GHSRBRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005061457-A1 | ORGANIC COMPOUNDS | SPEEDEL EXPERIMENTA AG (CH) | 2005-07-07 | — | — | WO | disclosed |