Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 3/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | PPP1CA | P62136 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | PPIA | P62937 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | NMT1 | P30419 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6270665 | 0.93 | LRRK2 (0.39) | MEN1KMT2ASMN1; SMN2GAALRRK2 | |
| SCHEMBL6271193 | 0.91 | KMT2A (0.41) | MEN1KMT2ASMN1; SMN2GAALRRK2 | |
| SCHEMBL6272458 | 0.86 | NLRP3 (0.40) | MEN1KMT2ASMN1; SMN2GAALRRK2 | |
| SCHEMBL6269042 | 0.83 | AKR1C3 (0.39) | KMT2ASMN1; SMN2GAALRRK2ALDH1A1 | |
| SCHEMBL6272705 | 0.83 | LRRK2 (0.39) | MEN1KMT2ASMN1; SMN2GAALRRK2 | |
| SCHEMBL6272989 | 0.82 | GAA (0.38) | MEN1KMT2ASMN1; SMN2GAALRRK2 | |
| SCHEMBL6274200 | 0.81 | LRRK2 (0.37) | MEN1KMT2ANPSR1LRRK2ALDH1A1 | |
| SCHEMBL6274196 | 0.81 | LRRK2 (0.37) | MEN1KMT2ANPSR1LRRK2ALDH1A1 | |
| SCHEMBL6272979 | 0.80 | POLB (0.41) | MEN1KMT2ASMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL6273572 | 0.80 | AKR1C3 (0.39) | KMT2ASMN1; SMN2GAALRRK2NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005110981-A1 | AMINOALCOHOL DERIVATIVES | ASTELLAS PHARMA INC. (JP) | 2005-11-24 | — | — | WO | disclosed |