Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 9/20 | 0.46 |
| ▸ | MAP3K12 | Q12852 | 7/20 | 0.39 |
| ▸ | RIPK1 | Q13546 | 4/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL627308 | 0.82 | PIK3CA (0.49) | PIK3CAMAP3K12RIPK1 | |
| SCHEMBL625421 | 0.81 | PIK3CA (0.52) | PIK3CAMAP3K12RIPK1 | |
| SCHEMBL625743 | 0.81 | PIM1 (0.42) | — | |
| SCHEMBL627208 | 0.79 | USP30 (0.33) | — | |
| SCHEMBL626245 | 0.79 | PIK3CA (0.46) | PIK3CAMAP3K12RIPK1 | |
| SCHEMBL627431 | 0.78 | PIK3CA (0.48) | PIK3CA | |
| SCHEMBL627019 | 0.77 | PIK3CA (0.47) | PIK3CAMAP3K12 | |
| SCHEMBL626122 | 0.76 | PIK3CA (0.45) | PIK3CA | |
| SCHEMBL624921 | 0.75 | PIK3CA (0.49) | PIK3CAMAP3K12RIPK1 | |
| SCHEMBL625127 | 0.75 | PIK3CA (0.48) | PIK3CARIPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012020215-A1 | AMINO- IMIDAZOLOTHIADIAZOLES FOR USE AS PROTEIN OR LIPID KINASE INHIBITORS | CENTRO NACIONAL DE INVESTIGACIONES ONCOLÓGICAS (CNIO) (ES) | 2012-02-16 | — | — | WO | disclosed |