Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 12/20 | 0.41 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.40 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.40 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.40 |
| ▸ | MME | P08473 | 1/20 | 0.40 |
| ▸ | ECE1 | P42892 | 1/20 | 0.40 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.38 |
| ▸ | MC4R | P32245 | 3/20 | 0.38 |
| ▸ | HRH1 | P35367 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6273137 | 1.00 | REN (0.41) | RENERAP2ERAP1LNPEPMME | |
| SCHEMBL6270159 | 0.88 | REN (0.49) | RENERAP2ERAP1LNPEPMME | |
| SCHEMBL6273980 | 0.85 | ERAP2 (0.53) | RENERAP2ERAP1LNPEPMME | |
| SCHEMBL6269554 | 0.83 | REN (0.56) | RENERAP2ERAP1LNPEPMME | |
| SCHEMBL8275264 | 0.82 | MMP2 (0.43) | RENERAP2ERAP1LNPEPMME | |
| SCHEMBL6271389 | 0.81 | PIN1 (0.46) | RENERAP2ERAP1LNPEPMME | |
| SCHEMBL6271395 | 0.81 | PIN1 (0.46) | RENERAP2ERAP1LNPEPMME | |
| SCHEMBL6270151 | 0.77 | ERAP2 (0.55) | RENERAP2ERAP1LNPEPMME | |
| SCHEMBL6273418 | 0.72 | REN (0.47) | RENERAP2ERAP1LNPEPMME | |
| SCHEMBL8276955 | 0.71 | ERAP2 (0.52) | RENERAP2ERAP1LNPEPMME |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005105843-A2 | HIV PROTEASE INHIBITORS | ARPIDA A/S (DK) | 2005-11-10 | — | — | WO | disclosed |