Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OGFRL1 | Q5TC84 | 7/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 5/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 5/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | ELANE | P08246 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL51466 | 0.78 | OGFRL1 (0.34) | OGFRL1OPRM1OPRK1OPRD1ALDH1A1 | |
| SCHEMBL13657351 | 0.78 | OGFRL1 (0.37) | OGFRL1OPRM1OPRK1OPRD1ALDH1A1 | |
| SCHEMBL62151 | 0.76 | ADORA3 (0.37) | OGFRL1OPRM1OPRK1OPRD1HPGD | |
| SCHEMBL52427 | 0.75 | ADORA3 (0.36) | OGFRL1OPRM1OPRK1OPRD1ALDH1A1 | |
| SCHEMBL63010 | 0.74 | OGFRL1 (0.33) | OGFRL1OPRM1OPRK1OPRD1ALDH1A1 | |
| SCHEMBL63621 | 0.72 | ROCK2 (0.38) | OGFRL1OPRM1OPRK1OPRD1MAPT | |
| SCHEMBL51560 | 0.71 | OGFRL1 (0.34) | OGFRL1OPRM1OPRK1OPRD1ALDH1A1 | |
| SCHEMBL52246 | 0.70 | HPGD (0.37) | OGFRL1OPRM1OPRK1OPRD1MAPT | |
| SCHEMBL61874 | 0.67 | ALDH1A1 (0.37) | OGFRL1OPRM1OPRK1OPRD1ALDH1A1 | |
| SCHEMBL52189 | 0.67 | OGFRL1 (0.32) | OGFRL1OPRM1OPRK1OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8129398-B2 | HIV integrase inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2012-03-06 | — | — | US | disclosed |