Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 3/20 | 0.41 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.41 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.37 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.37 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.36 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5734399 | 0.78 | HSD11B1 (0.41) | HSD11B1OPRM1OPRL1OPRD1OPRK1 | |
| SCHEMBL18554982 | 0.74 | HSD11B1 (0.35) | HSD11B1GRIN1GRIN2AGRIN2BCNR2 | |
| SCHEMBL5737096 | 0.74 | CNR1 (0.40) | CNR2HPGDHSD17B10ALDH1A1CYP1A2 | |
| SCHEMBL1097860 | 0.74 | MEN1 (0.45) | HSD11B1GRIN1GRIN2AGRIN2BOPRM1 | |
| SCHEMBL5763693 | 0.73 | HDAC4 (0.42) | OPRM1OPRL1OPRD1OPRK1ALDH1A1 | |
| SCHEMBL30685514 | 0.72 | OPRL1 (0.35) | OPRL1ALDH1A1PIK3CACYP1A2CYP2D6 | |
| SCHEMBL20446611 | 0.71 | SLC6A3 (0.40) | SLC6A2SLC6A4 | |
| SCHEMBL1515554 | 0.71 | HSD11B1 (0.48) | HSD11B1GRIN1GRIN2AGRIN2BCNR2 | |
| SCHEMBL29388865 | 0.71 | HSD11B1 (0.50) | HSD11B1GRIN1GRIN2AGRIN2BCNR2 | |
| SCHEMBL3671285 | 0.71 | HSD11B1 (0.50) | HSD11B1GRIN1GRIN2AGRIN2BCNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2005132746-A | PYRIDYLPYRROLIDINEDICARBOXAMIDE DERIVATIVE | TOKUYAMA CORP | 2005-05-26 | — | — | JP | disclosed |