Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.75 |
| ▸ | TSHR | P16473 | 2/20 | 0.75 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 3/20 | 0.34 |
| ▸ | CPB1 | P15086 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | LDHA | P00338 | 1/20 | 0.32 |
| ▸ | SRR | Q9GZT4 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 3/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 2/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Aconitic Acid SCHEMBL6273427 | 1.00 | KDM4E (0.75) | KDM4ETSHRCYP2C9RECQLHTT | |
| Aconitic Acid SCHEMBL8650635 | 1.00 | KDM4E (0.75) | KDM4ETSHRCYP2C9RECQLHTT | |
| Aconitic Acid SCHEMBL31252804 | 0.89 | KDM4E (0.86) | KDM4ETSHRRECQLCPB1ALOX15 | |
| Aconitic Acid SCHEMBL2022211 | 0.87 | TSHR (1.00) | KDM4ETSHRRECQLCPB1ALOX15 | |
| Aconitic Acid SCHEMBL219037 | 0.87 | TSHR (1.00) | KDM4ETSHRRECQLCPB1ALOX15 | |
| Aconitic Acid SCHEMBL1289876 | 0.87 | TSHR (1.00) | KDM4ETSHRRECQLCPB1ALOX15 | |
| Aconitic Acid SCHEMBL22334 | 0.87 | TSHR (1.00) | KDM4ETSHRRECQLCPB1ALOX15 | |
| Aconitic Acid SCHEMBL16935 | 0.87 | TSHR (1.00) | KDM4ETSHRRECQLCPB1ALOX15 | |
| Aconitic Acid SCHEMBL1275978 | 0.87 | TSHR (1.00) | KDM4ETSHRRECQLCPB1ALOX15 | |
| Aconitic Acid SCHEMBL27092737 | 0.85 | TSHR (0.78) | KDM4ETSHRRECQLCPB1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005123913-A2 | REVERSIBLY MODIFIED THERMOSTABLE ENZYME COMPOSITIONS AND METHODS OF MAKING AND USING THE SAME | NUSTAR LABORATORY (US) | 2005-12-29 | — | — | WO | disclosed |
| EP-0864639-A2 | A crystalline calcium carbonate builder encapsulated with a hydrotrope for use in detergent compositions | THE PROCTER & GAMBLE COMPANY (US) | 1998-09-16 | — | — | EP | disclosed |