Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 7/20 | 0.49 |
| ▸ | METAP1 | P53582 | 4/20 | 0.42 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HBB | P68871 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4221590 | 0.80 | ACHE (0.58) | ACHEMETAP1ALDH1A1HBBHSD17B10 | |
| SCHEMBL1855652 | 0.80 | ACHE (0.58) | ACHEMETAP1ALDH1A1HBBHSD17B10 | |
| SCHEMBL30022661 | 0.80 | ACHE (0.58) | ACHEMETAP1ALDH1A1HBBHSD17B10 | |
| SCHEMBL11523523 | 0.73 | ACHE (0.53) | ACHEMETAP1MAPTKMT2AKDM4E | |
| SCHEMBL5311960 | 0.71 | KMT2A (0.55) | ACHEMETAP1NOTUMMAPTKMT2A | |
| SCHEMBL19836626 | 0.71 | ALDH1A1 (0.54) | ACHEMETAP1ALDH1A1HBBHSD17B10 | |
| Trifluoromethanesulfonic Acid SCHEMBL28512188 | 0.71 | ACHE (0.44) | ACHEMETAP1ALDH1A1HBBHSD17B10 | |
| SCHEMBL29769613 | 0.69 | MAPT (0.49) | ACHEMETAP1ALDH1A1HBBHSD17B10 | |
| SCHEMBL6117763 | 0.69 | MAPT (0.49) | ACHEMETAP1ALDH1A1HBBHSD17B10 | |
| SCHEMBL856747 | 0.68 | ACHE (0.56) | ACHEMETAP1ALDH1A1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005097093-A1 | SLEEP INDUCING COMPOUNDS AND METHODS RELATING THERETO | NEUROCRINE BIOSCIENCES, INC. (US) | 2005-10-20 | — | — | WO | disclosed |