SCHEMBL6273593

SCHEMBL6273593

Cc1ccc(S(=O)(=O)OCCCCCCCCCCCCCCC(=O)Nc2c(C(C)C)cccc2C(C)C)cc1

nearest known ligand 0.52

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
NLRP3 Q96P20 1/20 0.52
SOAT1 P35610 2/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19386611 0.76 ALDH1A1 (0.44)
SCHEMBL28974745 0.76 ALDH1A1 (0.44)
SCHEMBL3464668 0.75 PSMD10 (0.47)
SCHEMBL8779472 0.75 PSMD10 (0.47)
SCHEMBL28546483 0.75 PSMD10 (0.47)
SCHEMBL25176596 0.75 PSMD10 (0.47)
SCHEMBL8427107 0.75 PSMD10 (0.47)
SCHEMBL13446628 0.75 PSMD10 (0.47)
SCHEMBL8779442 0.75 PSMD10 (0.47)
SCHEMBL26639631 0.75 PSMD10 (0.47)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0807627-B1 Anilide compounds as ACAT inhibitors KOWA CO (JP) 2005-12-28 EP disclosed
US-6825223-B2 ACYL COENZYME A CHOLESTEROL ACYLTRANSFERASE (ACAT) INHIBITORS; 2-SUBSTITUTED BENZIMIDAZOLE, BENZOXAZOLE, AND BENZOTHIAZOLES KOWA COMPANY, LTD. (JP) 2004-11-30 US disclosed
US-20020037910-A1 Novel anilide compounds and pharmaceutical compositions comprising them SHIBUYA KIMIYUKI (JP) 2002-03-28 US disclosed
US-6204278-B1 Anilide compounds, including use thereof in ACAT inhibitition KOWA COMPANY, LTD. (JP) 2001-03-20 US disclosed
EP-0807627-A2 Anilide compounds as ACAT inhibitors Kowa Company Ltd. (JP) 1997-11-19 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020037910-A1 Novel anilide compounds and pharmaceutical compositions comprising them ACAT1, LCAT, SOAT1 NLRP3 1037/4885SOAT1 3/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.