Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 3/20 | 0.42 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.41 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 2/20 | 0.40 |
| ▸ | TDP2 | O95551 | 2/20 | 0.40 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.39 |
| ▸ | OTUD7B | Q6GQQ9 | 3/20 | 0.38 |
| ▸ | IDO1 | P14902 | 2/20 | 0.38 |
| ▸ | HTR6 | P50406 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.38 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6277518 | 0.84 | PTPN1 (0.46) | MAOBTNKS2BRD4CREBBPMAOA | |
| SCHEMBL7121215 | 0.78 | TNKS2 (0.43) | MAOBTNKS2PTGER1BRD4CREBBP | |
| SCHEMBL7116577 | 0.78 | TNKS2 (0.43) | MAOBTNKS2PTGER1BRD4CREBBP | |
| SCHEMBL6282874 | 0.75 | HTR6 (0.39) | MAOBPTGER1TDP2MRGPRX4HTR6 | |
| SCHEMBL6278882 | 0.72 | ABCC9 (0.43) | BRD4CREBBPIDO1SIRT2 | |
| SCHEMBL7413976 | 0.69 | TNKS2 (0.43) | MAOBTNKS2PTGER1BRD4CREBBP | |
| SCHEMBL1330628 | 0.67 | MAOB (0.62) | MAOBMRGPRX4 | |
| SCHEMBL1978691 | 0.66 | MAOB (0.55) | MAOBPTGER1MRGPRX4PTGDR2 | |
| SCHEMBL7129137 | 0.66 | MAOB (0.58) | MAOBPTGER1MAOAMRGPRX4 | |
| SCHEMBL1980141 | 0.66 | MAOB (0.58) | MAOBPTGER1MRGPRX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6855726-B1 | Quinolones as serine protease inhibitors | WARNER-LAMBERT COMPANY LLC (US) | 2005-02-15 | — | — | US | disclosed |
| EP-1091955-A1 | QUINOLONES AS SERINE PROTEASE INHIBITORS | WARNER-LAMBERT COMPANY LLC (US) | 2001-04-18 | — | — | EP | disclosed |
| WO-1999050263-A1 | QUINOLONES AS SERINE PROTEASE INHIBITORS | WARNER-LAMBERT COMPANY (US) | 1999-10-07 | — | — | WO | disclosed |