Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.46 |
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29351451 | 0.85 | MAPT (0.63) | MAPTKDM4EALDH1A1MAPK1LMNA | |
| SCHEMBL303646 | 0.85 | MAPT (0.63) | MAPTKDM4EALDH1A1MAPK1LMNA | |
| SCHEMBL6275597 | 0.83 | HTT (0.58) | MAPTALDH1A1MAPK1LMNASMN1; SMN2 | |
| SCHEMBL1558275 | 0.76 | MAPT (0.58) | MAPTKDM4EALDH1A1LMNAGAA | |
| SCHEMBL10579820 | 0.75 | CXCR1 (0.57) | MAPTALDH1A1MAPK1LMNASMN1; SMN2 | |
| SCHEMBL2307463 | 0.75 | ALDH1A1 (0.54) | MAPTKDM4EALDH1A1MAPK1LMNA | |
| SCHEMBL17737257 | 0.75 | MAPT (0.45) | MAPTALDH1A1LMNASMN1; SMN2KMT2A | |
| Ethylamine SCHEMBL5152975 | 0.74 | MAPT (0.50) | MAPTKDM4EALDH1A1MAPK1LMNA | |
| SCHEMBL11159531 | 0.74 | MAPT (0.62) | MAPTKDM4EALDH1A1MAPK1LMNA | |
| SCHEMBL31045644 | 0.74 | CRHBP (0.52) | MAPTKDM4EALDH1A1MAPK1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114618457-A | Binitryl-substituted phenyl chromatographic stationary phase and preparation and application thereof | 中国科学院大连化学物理研究所 | 2022-06-14 | — | — | CN | disclosed |