Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | HTT | P42858 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6273009 | 0.81 | SIGMAR1 (0.36) | SIGMAR1 | |
| SCHEMBL28501995 | 0.76 | HTR2A (0.36) | SIGMAR1TP53HSD17B10 | |
| Hydrochloric Acid SCHEMBL3212771 | 0.75 | HTR6 (0.33) | SIGMAR1 | |
| SCHEMBL28496033 | 0.74 | SIGMAR1 (0.33) | SIGMAR1TP53HSD17B10 | |
| SCHEMBL3212779 | 0.72 | SIGMAR1 (0.33) | SIGMAR1 | |
| SCHEMBL2830663 | 0.72 | HTR2C (0.37) | SIGMAR1TP53HSD17B10 | |
| SCHEMBL27740455 | 0.71 | SIGMAR1 (0.38) | HTTKMT2AMEN1SIGMAR1TP53 | |
| SCHEMBL3212530 | 0.68 | GAA (0.43) | MAPTALDH1A1HTTKMT2AMEN1 | |
| SCHEMBL3204622 | 0.68 | SIGMAR1 (0.36) | ALDH1A1HTTKMT2AMEN1SIGMAR1 | |
| SCHEMBL6055955 | 0.68 | HTR2C (0.40) | SIGMAR1TP53HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1206427-B1 | CHIRAL LIGANDS, TRANSITION-METAL COMPLEXES THEREOF AND USES THEREOF IN ASYMMETRIC REACTIONS | PENN STATE RES FOUND (US) | 2005-11-09 | — | — | EP | disclosed |
| US-6828271-B2 | To form transition metal complexes which are used in such as asymmetric hydrogenation of imines, asymmetric hydride transfer reactions, hydrosilylation, hydroboration, hydrovinylation hydroformylation, allylic alkylation, etc. | THE PENN STATE RESEARCH FOUNDATION | 2004-12-07 | — | — | US | disclosed |
| US-20030163003-A1 | Chiral ligands, transition-metal complexes thereof and uses thereof in asymmetric reactions | THE PENN STATE RESEARCH FOUNDATION | 2003-08-28 | — | — | US | disclosed |
| US-6525210-B1 | Binaphthyl phospholanes, chelating phosphines and ferrocene complexes thereof | THE PENN STATE RESEARCH FOUNDATION | 2003-02-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030163003-A1 | Chiral ligands, transition-metal complexes thereof and uses thereof in asymmetric reactions | PFKFB3, PFKFB4, PFKFB2 | MAPT 4743/4885ALDH1A1 1474/4885HTT 2588/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.