Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1407249 | 0.75 | CYP1A2 (0.43) | ALDH1A1KDM4EMAPTHPGDMEN1 | |
| SCHEMBL2845262 | 0.69 | APLNR (0.58) | ALDH1A1MAPTSMN1; SMN2TSHRCYP1A2 | |
| SCHEMBL30105464 | 0.69 | APLNR (0.58) | ALDH1A1MAPTSMN1; SMN2TSHRCYP1A2 | |
| SCHEMBL29817411 | 0.65 | ESR1 (0.64) | ALDH1A1KDM4EMAPTHPGDMEN1 | |
| SCHEMBL3889569 | 0.65 | ESR1 (0.64) | ALDH1A1KDM4EMAPTHPGDMEN1 | |
| SCHEMBL31193485 | 0.64 | CA12 (0.56) | ALDH1A1MAPTHPGDMEN1KMT2A | |
| SCHEMBL7909509 | 0.64 | CA12 (0.56) | ALDH1A1MAPTHPGDMEN1KMT2A | |
| SCHEMBL1407660 | 0.64 | CYP1A1 (0.46) | ALDH1A1KDM4EMAPTHPGDMEN1 | |
| SCHEMBL1407566 | 0.64 | DRD1 (0.39) | ALDH1A1KDM4EMAPTHPGDMEN1 | |
| SCHEMBL2848289 | 0.63 | ALOX5 (0.56) | ALDH1A1MAPTSMN1; SMN2LMNAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005039582-A1 | METHODS OF TREATING ATHEROSCLEROSIS USING NF-kB INHIBITORS | WYETH (US) | 2005-05-06 | — | — | WO | disclosed |