Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APLNR | P35414 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CA7 | P43166 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.50 |
| ▸ | PPARG | P37231 | 1/20 | 0.49 |
| ▸ | PPARD | Q03181 | 1/20 | 0.49 |
| ▸ | PPARA | Q07869 | 1/20 | 0.49 |
| ▸ | CYP1A1 | P04798 | 3/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.48 |
| ▸ | CYP1B1 | Q16678 | 3/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30105464 | 1.00 | APLNR (0.58) | APLNRALDH1A1CYP3A4ALOX15TP53 | |
| SCHEMBL28763162 | 0.88 | PTPN1 (0.47) | APLNRALDH1A1CYP3A4ALOX15TP53 | |
| SCHEMBL2842624 | 0.86 | FLT3 (0.51) | APLNRALDH1A1CYP3A4ALOX15TP53 | |
| SCHEMBL2848332 | 0.86 | TSHR (0.47) | APLNRALDH1A1CYP3A4ALOX15TP53 | |
| SCHEMBL2841579 | 0.86 | PTPN1 (0.49) | APLNRALDH1A1CYP3A4ALOX15TP53 | |
| SCHEMBL2848289 | 0.85 | ALOX5 (0.56) | ALDH1A1CYP3A4ALOX15TP53TSHR | |
| SCHEMBL2096402 | 0.85 | ALDH1A1 (0.57) | APLNRALDH1A1CYP3A4ALOX15TP53 | |
| SCHEMBL2844393 | 0.84 | TUBB4A (0.47) | APLNRALDH1A1CYP3A4ALOX15TP53 | |
| SCHEMBL2846283 | 0.84 | MAPT (0.49) | ALDH1A1MAPTCNR2 | |
| SCHEMBL2844258 | 0.84 | CNR2 (0.50) | APLNRALDH1A1CYP3A4ALOX15TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0502141-A4 | PRINTABLE PAPER COATING COMPOSITION | — | 1992-11-19 | — | — | EP | claimed |
| EP-0502141-A1 | PRINTABLE PAPER COATING COMPOSITION | BASF CORPORATION (US) | 1992-09-09 | — | — | EP | claimed |
| WO-1992003288-A1 | PRINTABLE PAPER COATING COMPOSITION | BASF CORPORATION (US) | 1992-03-05 | — | — | WO | claimed |
| CN-108640808-B | Preparation method of ortho-trifluoromethyl substituted azide | 河北工业大学 | 2020-12-29 | — | — | CN | disclosed |
| US-9497963-B2 | Methods and compositions for control of gypsy moth, Lymantria dispar | SIMON FRASER UNIVERSITY (CA) | 2016-11-22 | — | — | US | disclosed |
| US-9497963-B2 | Methods and compositions for control of gypsy moth, Lymantria dispar | SIMON FRASER UNIVERSITY (CA) | 2016-11-22 | — | — | US | disclosed |
| US-9497963-B2 | Methods and compositions for control of gypsy moth, Lymantria dispar | SIMON FRASER UNIVERSITY (CA) | 2016-11-22 | — | — | US | disclosed |
| US-9125406-B2 | Methods and compositions for control of cabbage looper, trichoplusia ni | SIMON FRASER UNIVERSITY (CA) | 2015-09-08 | — | — | US | disclosed |
| US-20130131185-A1 | Methods and Compositions for Control of Cabbage Looper, Trichoplusia ni | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 2013-05-23 | — | — | US | disclosed |
| US-20130045178-A1 | METHODS AND COMPOSITIONS FOR CONTROL OF GYPSY MOTH, Lymantria dispar | SIMON FRASER UNIVERSITY (CA) | 2013-02-21 | — | — | US | disclosed |
| US-20130045178-A1 | METHODS AND COMPOSITIONS FOR CONTROL OF GYPSY MOTH, Lymantria dispar | SIMON FRASER UNIVERSITY (CA) | 2013-02-21 | — | — | US | disclosed |
| US-20100190865-A1 | METHODS AND COMPOSITIONS FOR CONTROL OF GYPSY MOTHS, Lymanria dispar | SIMON FRASER UNIVERSITY (CA) | 2010-07-29 | — | — | US | disclosed |
| US-20100190865-A1 | METHODS AND COMPOSITIONS FOR CONTROL OF GYPSY MOTHS, Lymanria dispar | SIMON FRASER UNIVERSITY (CA) | 2010-07-29 | — | — | US | disclosed |
| US-20100160451-A1 | METHODS AND COMPOSITIONS FOR CONTROL OF CABBAGE LOOPER, Trichoplusia ni | SIMON FRASER UNIVERSITY (CA) | 2010-06-24 | — | — | US | disclosed |
| EP-1767514-B1 | Process for the isomerisation of alkenylalkoxybenzenen | SYMRISE GMBH & CO KG (DE) | 2010-03-31 | — | — | EP | disclosed |
| US-20090069341-A1 | INHIBITORS OF HSP90 | CHENE PATRICK | 2009-03-12 | — | — | US | disclosed |
| EP-1776110-A1 | INHIBITORS OF HSP90 | Novartis AG (CH) | 2007-04-25 | — | — | EP | disclosed |
| US-20070073089-A1 | Process for the Isomerisation of Alkenyl Alkoxybenzenes | SYMRISE GMBH & CO. KG (DE) | 2007-03-29 | — | — | US | disclosed |
| EP-1767514-A1 | Process for the isomerisation of alkenylalkoxybenzenen | Symrise GmbH & Co. KG (DE) | 2007-03-28 | — | — | EP | disclosed |
| WO-2006010594-A1 | INHIBITORS OF HSP90 | NOVARTIS AG (CH) | 2006-02-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090069341-A1 | INHIBITORS OF HSP90 | HSP90AB1, HSP90B1, HSP90AA1 | APLNR 4843/4885ALDH1A1 2811/4885CYP3A4 3840/4885 |
| US-20130131185-A1 | Methods and Compositions for Control of Cabbage Looper, Trichoplusia ni | CDV3, ETV1, BOLA2; BOLA2B | APLNR 4143/4885ALDH1A1 2318/4885CYP3A4 2172/4885 |
| US-20130045178-A1 | METHODS AND COMPOSITIONS FOR CONTROL OF GYPSY MOTH, Lymantria dispar | L3MBTL3, L3MBTL4, L3MBTL1 | APLNR 3808/4885ALDH1A1 4074/4885CYP3A4 2941/4885 |
| US-20100190865-A1 | METHODS AND COMPOSITIONS FOR CONTROL OF GYPSY MOTHS, Lymanria dispar | L3MBTL3, L3MBTL4, L3MBTL1 | APLNR 3739/4885ALDH1A1 4132/4885CYP3A4 2892/4885 |
| US-20100160451-A1 | METHODS AND COMPOSITIONS FOR CONTROL OF CABBAGE LOOPER, Trichoplusia ni | CDV3, ETV1, TMSB4X | APLNR 4187/4885ALDH1A1 2444/4885CYP3A4 1839/4885 |
| US-20070073089-A1 | Process for the Isomerisation of Alkenyl Alkoxybenzenes | ADH1C, ADH1A, AKR7A2 | APLNR 2941/4885ALDH1A1 53/4885CYP3A4 40/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.