Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHKA | P35790 | 1/20 | 0.53 |
| ▸ | RXRA | P19793 | 1/20 | 0.47 |
| ▸ | RXRB | P28702 | 1/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 2/20 | 0.39 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.38 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
| ▸ | PGR | P06401 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2586836 | 0.84 | AGXT (0.45) | CHKAAOC3PTGS2 | |
| SCHEMBL1420024 | 0.80 | AGXT (0.52) | TAAR1AOC3PTGS2 | |
| SCHEMBL6477595 | 0.79 | CHKA (0.57) | CHKARXRARXRBTAAR1CNR1 | |
| SCHEMBL19043341 | 0.79 | CHKA (0.50) | CHKARXRARXRBTAAR1CNR1 | |
| SCHEMBL167780 | 0.78 | PNMT (0.56) | TAAR1AOC3 | |
| SCHEMBL19287148 | 0.78 | TAAR1 (0.65) | TAAR1MAOBPGR | |
| SCHEMBL410767 | 0.77 | PRKCI (0.56) | CHKARXRARXRBTAAR1CNR1 | |
| SCHEMBL4194656 | 0.76 | MAPK14 (0.40) | — | |
| SCHEMBL1513827 | 0.76 | HSD17B1 (0.54) | — | |
| SCHEMBL4207990 | 0.75 | NR1H4 (0.60) | CHKARXRARXRBCNR1NR1H4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005092062-A2 | COMPOUNDS FOR NEURODEGENERATIVE DISORDERS | MYRIAD GENETICS, INC. (US) | 2005-10-06 | — | — | WO | disclosed |