Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | PDGFRB | P09619 | 3/20 | 0.46 |
| ▸ | PDGFRA | P16234 | 3/20 | 0.46 |
| ▸ | MGAM | O43451 | 1/20 | 0.46 |
| ▸ | EGFR | P00533 | 1/20 | 0.45 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.45 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.45 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | BIRC5 | O15392 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | GPR3 | P46089 | 1/20 | 0.41 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.40 |
| ▸ | ACACB | O00763 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28026429 | 0.83 | ALDH1A1 (0.53) | ALDH1A1CYP1A2PDGFRBPDGFRAMGAM | |
| SCHEMBL4818276 | 0.81 | ALDH1A1 (0.63) | ALDH1A1CYP1A2PDGFRBPDGFRAMGAM | |
| SCHEMBL444107 | 0.80 | ALDH1A1 (0.62) | ALDH1A1CYP1A2PDGFRBPDGFRAMGAM | |
| Water SCHEMBL27871202 | 0.80 | ALDH1A1 (0.57) | ALDH1A1CYP1A2PDGFRBPDGFRAMGAM | |
| SCHEMBL444106 | 0.80 | ALDH1A1 (0.57) | ALDH1A1CYP1A2PDGFRBPDGFRAMGAM | |
| SCHEMBL29788946 | 0.80 | ALDH1A1 (0.57) | ALDH1A1CYP1A2PDGFRBPDGFRAMGAM | |
| SCHEMBL3084485 | 0.80 | ALDH1A1 (0.57) | ALDH1A1CYP1A2PDGFRBPDGFRAMGAM | |
| SCHEMBL63442 | 0.80 | ALDH1A1 (0.57) | ALDH1A1CYP1A2PDGFRBPDGFRAMGAM | |
| SCHEMBL232457 | 0.80 | ALDH1A1 (0.57) | ALDH1A1CYP1A2PDGFRBPDGFRAMGAM | |
| Methane SCHEMBL28479303 | 0.78 | ALDH1A1 (0.56) | ALDH1A1CYP1A2PDGFRBPDGFRAMGAM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005121160-A2 | 11, 12 CYCLIC THIOCARBAMATE MACROLIDE ANTIBACTERIAL AGENTS | JOHNSON & JOHNSON PHARMACEUTICAL RESEARCH & DEVELOPMENT (US) | 2005-12-22 | — | — | WO | disclosed |
| US-20050250713-A1 | 11,12-Cyclic thiocarbamate macrolide antibacterial agents | ZHU BIN | 2005-11-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050250713-A1 | 11,12-Cyclic thiocarbamate macrolide antibacterial agents | MRPL21, TTC14, MRPL12 | ALDH1A1 4517/4885CYP1A2 3457/4885PDGFRB 3649/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.