SCHEMBL6276958

SCHEMBL6276958

OCCCCCOB(O)c1cccc2cc3ccccc3cc12

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 3/20 0.37
KDM4E B2RXH2 4/20 0.36
ALDH1A1 P00352 4/20 0.36
GAA P10253 3/20 0.36
MAPT P10636 2/20 0.36
HPGD P15428 1/20 0.36
TSHR P16473 1/20 0.36
HSD17B10 Q99714 1/20 0.36
CNR1 P21554 2/20 0.35
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
HDAC1 Q13547 5/20 0.32
HDAC3 O15379 4/20 0.32
HDAC4 P56524 4/20 0.32
HDAC7 Q8WUI4 4/20 0.32
HDAC2 Q92769 4/20 0.32
HDAC10 Q969S8 4/20 0.32
HDAC11 Q96DB2 4/20 0.32
HDAC8 Q9BY41 4/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5952005 0.81 KDM4E (0.44) CNR2KDM4EALDH1A1GAAMAPT
SCHEMBL700808 0.77 ALDH1A1 (0.34) KDM4EALDH1A1GAAMAPTMEN1
SCHEMBL5953133 0.74 HTR1B (0.40) CNR2KDM4EALDH1A1GAAMAPT
SCHEMBL28558634 0.71 ALDH1A1 (0.39) KDM4EALDH1A1GAAMAPTHPGD
SCHEMBL829841 0.69 ALDH1A1 (0.46) KDM4EALDH1A1GAAMAPTHPGD
SCHEMBL5951121 0.69 CA1 (0.50) CNR2KDM4EALDH1A1MAPTCNR1
SCHEMBL700686 0.68 HTR2A (0.36) KDM4EALDH1A1MAPTHPGDHSD17B10
SCHEMBL5953023 0.68 PTPN1 (0.31)
SCHEMBL28859138 0.68 HTR1B (0.53) CNR2KDM4EALDH1A1CNR1MEN1
SCHEMBL20678497 0.67 CNR2 (0.48) CNR2ALDH1A1HSD17B10CNR1HDAC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6927246-B2 Polymers functionalized with fluorescent boronate motifs and methods for making them MEDTRONIC MINIMED, INC. (US) 2005-08-09 US disclosed
US-6766183-B2 IMPLANTABLE BIOSENSOR; DETECTING AND MEASURING IN VIVO GLUCOSE CONCENTRATIONS MEDTRONIC MINIMED, INC. 2004-07-20 US disclosed
US-20020197724-A1 Polymers functionalized with fluorescent boronate motifs and methods for making them MEDTRONIC MINIMED, INC. 2002-12-26 US disclosed
US-20020193672-A1 Long wave fluorophore sensor compounds and other fluorescent sensor compounds in polymers LAWRENCE LIVERMORE NATIONAL SECURITY, LLC 2002-12-19 US disclosed
WO-2002066986-A2 POLYMERS FUNCTIONALIZED WITH FLUORESCENT BORONATE MOTIFS MEDTRONIC MINIMED, INC. (US) 2002-08-29 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020193672-A1 Long wave fluorophore sensor compounds and other fluorescent sensor compounds in polymers INSR, IRS1, IGF2R CNR2 3800/4885KDM4E 3433/4885ALDH1A1 2136/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.