Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | HTR1D | P28221 | 1/20 | 0.30 |
| ▸ | HTR1B | P28222 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL700687 | 0.80 | L3MBTL1 (0.38) | ALDH1A1KDM4ERECQLMEN1MAPT | |
| SCHEMBL6276958 | 0.77 | CNR2 (0.37) | ALDH1A1KDM4EGAAMEN1MAPT | |
| SCHEMBL14716623 | 0.73 | ALDH1A1 (0.36) | ALDH1A1KDM4EGAARECQL | |
| SCHEMBL28558634 | 0.73 | ALDH1A1 (0.39) | ALDH1A1KDM4EGAAMEN1MAPT | |
| SCHEMBL829841 | 0.71 | ALDH1A1 (0.46) | ALDH1A1KDM4EGAAMEN1MAPT | |
| SCHEMBL5953133 | 0.70 | HTR1B (0.40) | ALDH1A1KDM4EGAARECQLMEN1 | |
| SCHEMBL1479148 | 0.69 | ALDH1A1 (0.46) | ALDH1A1KDM4EGAAMEN1MAPT | |
| SCHEMBL1138975 | 0.69 | ALDH1A1 (0.42) | ALDH1A1KDM4EGAARECQLMEN1 | |
| SCHEMBL27554043 | 0.68 | HTR1B (0.51) | ALDH1A1KDM4ERECQLMEN1KMT2A | |
| SCHEMBL28715754 | 0.67 | ALDH1A1 (0.47) | ALDH1A1KDM4EGAAMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8124249-B2 | Derivatives of fused aromatic systems; stability; sublimation stability; easy to purify due to better solubilty; easy reproducibility because do not form isomers | MERCK PATENT GMBH (DE) | 2012-02-28 | — | — | US | disclosed |
| US-20080171225-A1 | Novel Materials For Organic Electroluminescent Devices | MERCK PATENT GMBH (DE) | 2008-07-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080171225-A1 | Novel Materials For Organic Electroluminescent Devices | OR10J3, EML4, TYR | ALDH1A1 1325/4885KDM4E 1657/4885GAA 2810/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.