SCHEMBL6277013

SCHEMBL6277013

C=CC(C(=O)O)c1nccs1

nearest known ligand 0.38

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
CTSA P10619 14/20 0.38
ALDH1A1 P00352 1/20 0.36
HTT P42858 1/20 0.34
ADAM17 P78536 1/20 0.33
NPC1 O15118 1/20 0.33
RAB9A P51151 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10824243 0.84 CTSA (0.38) CTSAALDH1A1HTTADAM17NPC1
SCHEMBL10348818 0.79 CTSA (0.36) CTSAALDH1A1HTTNPC1RAB9A
SCHEMBL2042559 0.76 CTSA (0.36) CTSAALDH1A1
SCHEMBL9370321 0.73
SCHEMBL909602 0.72 ALDH1A1 (0.44) CTSAALDH1A1HTTNPC1RAB9A
SCHEMBL1582982 0.72 GRIK1 (0.40) CTSAALDH1A1ADAM17NPC1RAB9A
SCHEMBL2398682 0.72 CTSA (0.40) CTSAALDH1A1ADAM17NPC1RAB9A
SCHEMBL11083464 0.72 GRIK1 (0.40) CTSAALDH1A1ADAM17NPC1RAB9A
SCHEMBL27423951 0.72 GRIK1 (0.40) CTSAALDH1A1ADAM17NPC1RAB9A
Hydrochloric Acid SCHEMBL11087078 0.70 GRIK1 (0.40) CTSAALDH1A1ADAM17NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2005115148-A1 3-ARYL-3-HYDROXY-2-METHYLENEPROPIONIC ACID ESTERS AS FUNGICIDES CROPSOLUTION, INC. (US) 2005-12-08 WO disclosed