Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.58 |
| ▸ | HPGD | P15428 | 3/20 | 0.58 |
| ▸ | USP2 | O75604 | 3/20 | 0.58 |
| ▸ | NPC1 | O15118 | 1/20 | 0.58 |
| ▸ | TP53 | P04637 | 3/20 | 0.57 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.56 |
| ▸ | LMNA | P02545 | 6/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.51 |
| ▸ | MEN1 | O00255 | 7/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.51 |
| ▸ | HTT | P42858 | 5/20 | 0.50 |
| ▸ | MAPT | P10636 | 5/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | ESR1 | P03372 | 1/20 | 0.49 |
| ▸ | CRHBP | P24387 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL628093 | 0.85 | ALDH1A1 (0.59) | ALDH1A1HSD17B10SMN1; SMN2HPGDUSP2 | |
| SCHEMBL624677 | 0.80 | GCK (0.44) | ALDH1A1HSD17B10SMN1; SMN2HPGDUSP2 | |
| SCHEMBL627134 | 0.71 | ACP1 (0.50) | ALDH1A1SMN1; SMN2HPGDNPC1TP53 | |
| SCHEMBL8260317 | 0.69 | KMT2A (0.63) | ALDH1A1HSD17B10SMN1; SMN2HPGDUSP2 | |
| SCHEMBL5875524 | 0.69 | KMT2A (0.63) | ALDH1A1HSD17B10SMN1; SMN2HPGDUSP2 | |
| SCHEMBL3562541 | 0.68 | GCK (0.71) | ALDH1A1HSD17B10SMN1; SMN2HPGDUSP2 | |
| SCHEMBL2655003 | 0.68 | GCK (0.71) | ALDH1A1HSD17B10SMN1; SMN2HPGDUSP2 | |
| SCHEMBL16689133 | 0.68 | ALDH1A1 (1.00) | ALDH1A1HSD17B10SMN1; SMN2HPGDUSP2 | |
| SCHEMBL2655726 | 0.68 | GCK (0.70) | ALDH1A1HSD17B10SMN1; SMN2HPGDUSP2 | |
| SCHEMBL3563432 | 0.68 | GCK (0.70) | ALDH1A1HSD17B10SMN1; SMN2HPGDUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012020357-A1 | ACETAMIDE COMPOUNDS, THEIR PROCESS AND PHARMACEUTICAL APPLICATION | ADVINUS THERAPEUTICS LTD. (IN) | 2012-02-16 | — | — | WO | claimed |
| WO-2012020357-A1 | ACETAMIDE COMPOUNDS, THEIR PROCESS AND PHARMACEUTICAL APPLICATION | ADVINUS THERAPEUTICS LTD. (IN) | 2012-02-16 | — | — | WO | disclosed |