SCHEMBL6277276

SCHEMBL6277276

O=C1C=CC(=O)N1C1CCc2ccccc21

nearest known ligand 0.48

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
HSD11B1 P28845 2/20 0.46
CHRNA7 P36544 1/20 0.45
GPR84 Q9NQS5 1/20 0.44
SRD5A1 P18405 2/20 0.43
OPRM1 P35372 2/20 0.42
OPRK1 P41145 2/20 0.42
OPRL1 P41146 2/20 0.42
CYP11B2 P19099 1/20 0.42
OPRD1 P41143 1/20 0.42
IDO1 P14902 1/20 0.41
PDPK1 O15530 1/20 0.41
MAOB P27338 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10697018 0.81 OPRM1 (0.41) CHRNA7OPRM1OPRK1OPRL1
SCHEMBL15028540 0.81 CRBN (0.57) HSD11B1CHRNA7GPR84OPRM1
SCHEMBL30703123 0.81 CRBN (0.57) HSD11B1CHRNA7GPR84OPRM1
SCHEMBL2557698 0.81 CRBN (0.57) HSD11B1CHRNA7GPR84OPRM1
SCHEMBL10159056 0.79 OPRK1 (0.48) HSD11B1CHRNA7GPR84SRD5A1OPRM1
SCHEMBL32665475 0.77 ESR1 (0.44) OPRM1OPRK1
SCHEMBL30077049 0.74 CHRNA7 (0.65) HSD11B1CHRNA7GPR84OPRM1OPRK1
SCHEMBL7878773 0.74 CHRNA7 (0.65) HSD11B1CHRNA7GPR84OPRM1OPRK1
SCHEMBL7878455 0.74 CHRNA7 (0.65) HSD11B1CHRNA7GPR84OPRM1OPRK1
SCHEMBL30077103 0.74 CHRNA7 (0.65) HSD11B1CHRNA7GPR84OPRM1OPRK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114262437-B Modified bismaleimide prepolymer, resin composition thereof, prepreg, laminated board and metal foil laminated board 苏州生益科技有限公司 2023-11-10 CN disclosed
CN-114316264-B Modified bismaleimide prepolymer, resin composition and application thereof 苏州生益科技有限公司 2023-10-27 CN disclosed
WO-2023190118-A1 RESIN COMPOSITION, PREPREG, RESIN SHEET, LAMINATED PLATE, METAL FOIL-CLAD LAMINATED PLATE, AND PRINTED WIRING BOARD 三菱瓦斯化学株式会社 2023-10-05 WO disclosed
JP-2005179209-A OPTICALLY ACTIVE MALEIMIDE DERIVATIVE, OPTICALLY ACTIVE POLYMALEIMIDE DERIVATIVE, METHOD FOR PRODUCING THE SAME, SEPARATING AGENT COMPRISING THE OPTICALLY ACTIVE POLYMALEIMIDE DERIVATIVE, AND METHOD FOR SEPARATING OPTICALLY ACTIVE COMPOUND BY USING THE SAME TOSOH CORP 2005-07-07 JP disclosed