Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIN1 | Q13526 | 3/20 | 0.75 |
| ▸ | FKBP1A | P62942 | 17/20 | 0.63 |
| ▸ | FKBP4 | Q02790 | 1/20 | 0.48 |
| ▸ | FKBP5 | Q13451 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6267180 | 0.87 | FKBP1A (0.61) | PIN1FKBP1A | |
| SCHEMBL6274567 | 0.86 | PIN1 (1.00) | PIN1FKBP1AFKBP4FKBP5 | |
| SCHEMBL6272176 | 0.84 | PIN1 (0.53) | PIN1FKBP1A | |
| SCHEMBL6269509 | 0.81 | PIN1 (0.49) | PIN1FKBP1A | |
| SCHEMBL7506392 | 0.80 | FKBP1A (0.73) | PIN1FKBP1AFKBP4FKBP5 | |
| SCHEMBL7227496 | 0.80 | FKBP1A (0.73) | PIN1FKBP1AFKBP4FKBP5 | |
| SCHEMBL7227728 | 0.77 | FKBP1A (0.65) | PIN1FKBP1AFKBP4FKBP5 | |
| SCHEMBL7504251 | 0.76 | FKBP1A (0.66) | PIN1FKBP1AFKBP4FKBP5 | |
| SCHEMBL6270558 | 0.76 | PIN1 (0.72) | PIN1FKBP1A | |
| SCHEMBL7221865 | 0.76 | FKBP1A (0.66) | PIN1FKBP1AFKBP4FKBP5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1603926-A1 | PHOSPHATE/SULFATE ESTER COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS FOR INHIBITING PROTEIN INTERACTING NIMA (PIN1) | PFIZER INC. (US) | 2005-12-14 | — | — | EP | disclosed |
| US-20050250742-A1 | Phosphate/sulfate ester compounds and pharmaceutical composition for inhibiting protein interacting NIMA (PIN1) | PFIZER INC. | 2005-11-10 | — | — | US | disclosed |
| WO-2004087720-A1 | PHOSPHATE/SULFATE ESTER COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS FOR INHIBITING PROTEIN INTERACTING NIMA (PIN1) | PFIZER INC. (US) | 2004-10-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050250742-A1 | Phosphate/sulfate ester compounds and pharmaceutical composition for inhibiting protein interacting NIMA (PIN1) | PIN1, PSTPIP2, NIM1K | PIN1 1/4885FKBP1A 21/4885FKBP4 58/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.