Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FKBP1A | P62942 | 18/20 | 0.73 |
| ▸ | PIN1 | Q13526 | 2/20 | 0.59 |
| ▸ | FKBP4 | Q02790 | 1/20 | 0.58 |
| ▸ | FKBP5 | Q13451 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7227496 | 1.00 | FKBP1A (0.73) | FKBP1APIN1FKBP4FKBP5 | |
| SCHEMBL7227728 | 0.82 | FKBP1A (0.65) | FKBP1APIN1FKBP4FKBP5 | |
| SCHEMBL7219542 | 0.82 | FKBP1A (0.80) | FKBP1A | |
| SCHEMBL7507945 | 0.82 | FKBP1A (0.80) | FKBP1A | |
| SCHEMBL6277972 | 0.80 | PIN1 (0.75) | FKBP1APIN1FKBP4FKBP5 | |
| SCHEMBL7504251 | 0.79 | FKBP1A (0.66) | FKBP1APIN1FKBP4FKBP5 | |
| SCHEMBL7221865 | 0.79 | FKBP1A (0.66) | FKBP1APIN1FKBP4FKBP5 | |
| SCHEMBL7228304 | 0.79 | FKBP1A (0.77) | FKBP1APIN1 | |
| SCHEMBL5966132 | 0.78 | FKBP1A (1.00) | FKBP1A | |
| SCHEMBL4124896 | 0.77 | FKBP1A (0.60) | FKBP1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1237869-A1 | COMPOUNDS, COMPOSITIONS, AND METHODS FOR STIMULATING NEURONAL GROWTH AND ELONGATION | AGOURON PHARMACEUTICALS, INC. (US) | 2002-09-11 | — | — | EP | disclosed |
| WO-2001040185-A1 | COMPOUNDS, COMPOSITIONS, AND METHODS FOR STIMULATING NEURONAL GROWTH AND ELONGATION | AGOURON PHARMACEUTICALS, INC. (US) | 2001-06-07 | — | — | WO | disclosed |