Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 7/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | LIG1 | P18858 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.33 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.33 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6278576 | 0.94 | ALDH1A1 (0.45) | CYP3A4TSHRALDH1A1CYP2C19HSD17B10 | |
| SCHEMBL6284490 | 0.93 | CYP3A4 (0.41) | CYP3A4TSHRALDH1A1CYP2C19HSD17B10 | |
| SCHEMBL6284493 | 0.88 | MAPK1 (0.39) | CYP3A4ALDH1A1CYP2C19HSD17B10TDP1 | |
| SCHEMBL6278573 | 0.84 | CA12 (0.40) | TSHRALDH1A1CYP2C19L3MBTL1TP53 | |
| SCHEMBL6281232 | 0.82 | SMN1; SMN2 (0.38) | CYP3A4TSHRALDH1A1CYP2C19TDP1 | |
| SCHEMBL6284505 | 0.80 | ALDH1A1 (0.41) | ALDH1A1TDP1LMNASMN1; SMN2 | |
| SCHEMBL6278574 | 0.79 | ALDH1A1 (0.40) | TSHRALDH1A1CYP2C19TDP1L3MBTL1 | |
| SCHEMBL6281238 | 0.77 | LMNA (0.38) | TP53LMNANPC1KDM4ESMN1; SMN2 | |
| SCHEMBL11026389 | 0.76 | — | — | |
| SCHEMBL6284511 | 0.76 | LMNA (0.45) | ALDH1A1TDP1LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6846900-B2 | POLYVALENT CARBOXYLIC ACID ESTER, PROCESS FOR PRODUCING THE CARBOXYLIC ACID ESTER, PLASTIC LENS COMPOSITION USING THE CARBOXYLIC ESTER, PLASTIC LENS OBTAINED BY CURING THE COMPOSITION AND PROCESS FOR PRODUCING THE PLASTIC LENS | SHOWA DENKO K.K. (JP) | 2005-01-25 | — | — | US | disclosed |
| US-20030144447-A1 | Novel polyvalent carboxylic acid ester and their use in plastic lens compositions | SHOW A DENKO K.K. (JP) | 2003-07-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030144447-A1 | Novel polyvalent carboxylic acid ester and their use in plastic lens compositions | VCL, VIM, CRYAA | CYP3A4 1715/4885TSHR 2116/4885ALDH1A1 1516/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.