Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.58 |
| ▸ | LMNA | P02545 | 6/20 | 0.58 |
| ▸ | USP2 | O75604 | 2/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | GAA | P10253 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.52 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6277778 | 0.87 | SMN1; SMN2 (0.76) | L3MBTL1ALDH1A1LMNAUSP2ALOX15 | |
| SCHEMBL6278105 | 0.85 | ALDH1A1 (0.52) | L3MBTL1ALDH1A1LMNAUSP2ALOX15 | |
| SCHEMBL6279592 | 0.84 | ALDH1A1 (0.69) | L3MBTL1ALDH1A1LMNAUSP2ALOX15 | |
| SCHEMBL6280684 | 0.84 | PKM (0.55) | L3MBTL1ALDH1A1LMNAUSP2ALOX15 | |
| SCHEMBL6269345 | 0.83 | ALDH1A1 (0.50) | L3MBTL1ALDH1A1LMNAUSP2ALOX15 | |
| SCHEMBL1702875 | 0.82 | TDP1 (0.69) | ALDH1A1LMNAUSP2ALOX15HSD17B10 | |
| SCHEMBL6280412 | 0.80 | ALDH1A1 (0.56) | L3MBTL1ALDH1A1LMNAUSP2SMN1; SMN2 | |
| SCHEMBL24209696 | 0.78 | NPSR1 (0.67) | L3MBTL1ALDH1A1LMNAUSP2SMN1; SMN2 | |
| SCHEMBL1702494 | 0.78 | ALDH1A1 (0.64) | L3MBTL1ALDH1A1LMNAHSD17B10SMN1; SMN2 | |
| SCHEMBL6276510 | 0.77 | TDP1 (0.55) | L3MBTL1ALDH1A1LMNAUSP2ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9566284-B2 | Agents and methods for treating ischemic and other diseases | NONO INC. (CA) | 2017-02-14 | — | — | US | disclosed |
| WO-2005115147-A2 | HIV REVERSE TRANSCRIPTASE INHIBITORS | MERCK & CO., INC. (US) | 2005-12-08 | — | — | WO | disclosed |