Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 4/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.55 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.51 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.51 |
| ▸ | P4HB | P07237 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | CA1 | P00915 | 6/20 | 0.48 |
| ▸ | CA2 | P00918 | 6/20 | 0.48 |
| ▸ | CA9 | Q16790 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6278105 | 0.85 | ALDH1A1 (0.52) | ALDH1A1L3MBTL1GAAAPOBEC3AAPOBEC3G | |
| SCHEMBL6269345 | 0.85 | ALDH1A1 (0.50) | PKMALDH1A1L3MBTL1GAAAPOBEC3A | |
| SCHEMBL6279656 | 0.84 | L3MBTL1 (0.67) | ALDH1A1L3MBTL1GAAAPOBEC3AAPOBEC3G | |
| SCHEMBL6276438 | 0.83 | PKM (0.52) | PKMALDH1A1L3MBTL1GAAAPOBEC3A | |
| SCHEMBL6277778 | 0.78 | SMN1; SMN2 (0.76) | ALDH1A1L3MBTL1GAAAPOBEC3GTDP1 | |
| SCHEMBL1702875 | 0.77 | TDP1 (0.69) | ALDH1A1HTTTDP1LMNASMN1; SMN2 | |
| SCHEMBL6279592 | 0.75 | ALDH1A1 (0.69) | PKMALDH1A1L3MBTL1GAAHTT | |
| SCHEMBL6280412 | 0.75 | ALDH1A1 (0.56) | PKMALDH1A1L3MBTL1GAAHTT | |
| SCHEMBL12459464 | 0.74 | ALDH1A1 (0.56) | PKMALDH1A1GAATDP1CA1 | |
| SCHEMBL6276510 | 0.74 | TDP1 (0.55) | ALDH1A1L3MBTL1GAATDP1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005115147-A2 | HIV REVERSE TRANSCRIPTASE INHIBITORS | MERCK & CO., INC. (US) | 2005-12-08 | — | — | WO | disclosed |