SCHEMBL6280046

SCHEMBL6280046

C=CCc1ccc(CCc2ccc(C=C)cc2)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.50
CYP3A4 P08684 3/20 0.47
SMN1; SMN2 Q16637 3/20 0.47
TSHR P16473 2/20 0.47
TP53 P04637 1/20 0.47
ALOX15 P16050 1/20 0.47
ALOX12 P18054 1/20 0.47
XDH P47989 1/20 0.42
MAPT P10636 4/20 0.41
MEN1 O00255 3/20 0.41
GAA P10253 3/20 0.41
KMT2A Q03164 3/20 0.41
PPARG P37231 2/20 0.41
PPARD Q03181 2/20 0.41
KDM4E B2RXH2 2/20 0.41
GABRA1 P14867 2/20 0.41
CNR1 P21554 2/20 0.41
CNR2 P34972 2/20 0.41
GABRB2 P47870 2/20 0.41
ALDH2 P05091 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL278055 0.93 ALDH1A1 (0.58) ALDH1A1CYP3A4SMN1; SMN2TSHRTP53
SCHEMBL1647493 0.88 ALDH1A1 (0.65) ALDH1A1TSHRTP53MAPTMEN1
SCHEMBL50012 0.88 ALDH1A1 (0.65) ALDH1A1TSHRTP53MAPTMEN1
SCHEMBL6284374 0.88 ALDH1A1 (0.56) ALDH1A1CYP3A4SMN1; SMN2TSHRTP53
SCHEMBL173301 0.80 ALDH1A1 (0.64) ALDH1A1CYP3A4SMN1; SMN2TSHRTP53
SCHEMBL9806380 0.79 ALDH1A1 (0.59) ALDH1A1SMN1; SMN2TSHRALOX15ALOX12
SCHEMBL346414 0.79 ALDH1A1 (0.52) ALDH1A1CYP3A4SMN1; SMN2TSHRTP53
SCHEMBL177912 0.78 ALDH1A1 (0.58) ALDH1A1TSHRMEN1KMT2APPARA
SCHEMBL1140696 0.78 ALDH1A1 (0.58) ALDH1A1CYP3A4TSHRTP53ALOX15
SCHEMBL10908422 0.77 ESR1 (0.64) ALDH1A1CYP3A4SMN1; SMN2TSHRTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-100543981-C Semiconductor element and semiconductor package HITACHI LTD (JP) 2009-09-23 CN disclosed
US-6855952-B2 Semiconductor device and semiconductor package HITACHI, LTD. (JP) 2005-02-15 US disclosed
CN-1479373-A Semiconductor element and semiconductor package ������������ʽ���� 2004-03-03 CN disclosed
US-20040038021-A1 Semiconductor device and semiconductor package HITACHI, LTD. (JP) 2004-02-26 US disclosed