SCHEMBL994055

SCHEMBL994055

O=[N+]([O-])c1ccc(Cn2cncn2)cc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 6/20 0.57
HDAC1 Q13547 1/20 0.52
HDAC6 Q9UBN7 1/20 0.52
TGM2 P21980 1/20 0.50
POLB P06746 3/20 0.47
ATM Q13315 2/20 0.46
LMNA P02545 2/20 0.46
MAPT P10636 2/20 0.46
SMN1; SMN2 Q16637 2/20 0.46
NPC1 O15118 1/20 0.46
TP53 P04637 1/20 0.46
PKM P14618 1/20 0.46
HPGD P15428 1/20 0.46
HTT P42858 1/20 0.46
RAB9A P51151 1/20 0.46
KMT2A Q03164 3/20 0.46
MEN1 O00255 2/20 0.45
KDM4E B2RXH2 1/20 0.45
MAPK1 P28482 1/20 0.45
HSP90AA1 P07900 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6034201 0.84 CYP19A1 (0.57) CYP19A1POLBPKMKMT2A
SCHEMBL17159812 0.82 CYP19A1 (0.80) CYP19A1HDAC1HDAC6
SCHEMBL2728791 0.82 CYP19A1 (0.57) CYP19A1HDAC1HDAC6ATMLMNA
SCHEMBL5655760 0.82 KCNJ1 (0.54) CYP19A1POLBPKMKMT2A
SCHEMBL9525426 0.80 KDM4E (0.50) CYP19A1HDAC1HDAC6POLBPKM
SCHEMBL15688800 0.77 CYP19A1 (0.71) CYP19A1HDAC1HDAC6
SCHEMBL6280404 0.77 PKM (0.49) CYP19A1HDAC1HDAC6MAPTPKM
SCHEMBL10247588 0.76 CYP19A1 (0.59) CYP19A1MAPTKDM4EHSP90AA1
SCHEMBL3235365 0.75 CYP19A1 (0.69) CYP19A1HDAC1HDAC6
SCHEMBL11354103 0.75 CYP19A1 (0.69) CYP19A1HDAC1HDAC6POLBSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 71 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090062550-A1 Process for the Large Scale Production of Rizatriptan Benzoate MATRIX LABORATORIES LTD (IN) 2009-03-05 US claimed
WO-2025262152-A1 CONDUCTIVE POLYMER DISPERSIONS FOR IMPROVED STABILITY PERFORMANCE OF CAPACITORS HERAEUS EPURIO GMBH (DE) 2025-12-26 WO disclosed
EP-4668303-A1 CONDUCTIVE POLYMER DISPERSIONS FOR IMPROVED STABILITY PERFORMANCE OF CAPACITORS Heraeus Epurio GmbH (DE) 2025-12-24 EP disclosed
US-11935803-B2 Resin composition, laminate, semiconductor wafer with resin composition layer, substrate for mounting semiconductor with resin composition layer and semiconductor device MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2024-03-19 US disclosed
CN-112004845-B Resin composition, laminate, semiconductor wafer with resin composition layer, substrate, and semiconductor device 三菱瓦斯化学株式会社 2022-05-31 CN disclosed
US-20210277221-A1 RESIN COMPOSITION, LAMINATE, SEMICONDUCTOR WAFER WITH RESIN COMPOSITION LAYER, SUBSTRATE FOR MOUNTING SEMICONDUCTOR WITH RESIN COMPOSITION LAYER AND SEMICONDUCTOR DEVICE MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2021-09-09 US disclosed
EP-3786200-A1 RESIN COMPOSITION, LAMINATE, RESIN COMPOSITION LAYER-ATTACHED SEMICONDUCTOR WAFER, SUBSTRATE FOR MOUNTING RESIN COMPOSITION LAYER-ATTACHED SEMICONDUCTOR, AND SEMICONDUCTOR DEVICE MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2021-03-03 EP disclosed
CN-112004845-A Resin composition, laminate, semiconductor wafer with resin composition layer, substrate for mounting semiconductor with resin composition layer, and semiconductor device 三菱瓦斯化学株式会社 2020-11-27 CN disclosed
EP-1224170-B9 6-POSITION SUBSTITUTED INDOLINE, PRODUCTION AND USE THEREOF AS A MEDICAMENT BOEHRINGER INGELHEIM PHARMA (DE) 2017-11-22 EP disclosed
US-8431592-B2 1,3-dihydro-imidazo[4,5-c]quinolin-2-ones as lipid kinase inhibitors NOVARTIS AG (CH) 2013-04-30 US disclosed
EP-0651748-A1 PROCESS FOR PREPARING INDOLE DERIVATIVES CONTAINING A 1,2,4-TRIAZOL-1-YL SUBSTITUENT. MERCK SHARP & DOHME (GB) 1995-05-10 EP disclosed
EP-0651749-A1 IMIDAZOLE, TRIAZOLE AND TETRAZOLE DERIVATIVES MERCK SHARP & DOHME LTD. (GB) 1995-05-10 EP disclosed
EP-0630374-A1 IMIDAZOLE, TRIAZOLE AND TETRAZOLE DERIVATIVES MERCK SHARP & DOHME LTD. (GB) 1994-12-28 EP disclosed
US-5298520-A Triazole containing indole derivatives MERCK SHARP & DOHME LIMITED (GB) 1994-03-29 US disclosed
WO-1994002477-A1 IMIDAZOLE, TRIAZOLE AND TETRAZOLE DERIVATIVES MERCK SHARP & DOHME LIMITED (GB) 1994-02-03 WO disclosed
WO-1994002476-A1 PROCESS FOR PREPARING INDOLE DERIVATIVES CONTAINING A 1,2,4-TRIAZOL-1-YL SUBSTITUENT MERCK SHARP & DOHME LIMITED (GB) 1994-02-03 WO disclosed
WO-1993025547-A1 THE SULPHATE SALT OF A SUBSTITUTED TRIAZOLE, PHARMACEUTICAL COMPOSITIONS THEREOF, AND THEIR USE IN THERAPY MERCK SHARP & DOHME LIMITED (GB) 1993-12-23 WO disclosed
EP-0573221-A1 The sulphate salt of a substituted triazole, pharmaceutical compositions thereof, and their use in therapy MERCK SHARP & DOHME LTD. (GB) 1993-12-08 EP disclosed
WO-1993018029-A1 IMIDAZOLE, TRIAZOLE AND TETRAZOLE DERIVATIVES MERCK SHARP & DOHME LIMITED (GB) 1993-09-16 WO disclosed
EP-0497512-A2 Imidazole, triazole and tetrazole derivatives MERCK SHARP & DOHME LTD. (GB) 1992-08-05 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090062550-A1 Process for the Large Scale Production of Rizatriptan Benzoate DPP4, HTR3A, SI CYP19A1 2017/4885HDAC1 107/4885HDAC6 435/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.