SCHEMBL6280436

SCHEMBL6280436

CC(=CC(C)(CC(C)(C)c1ccc(O)cc1)c1ccc(O)cc1)c1ccc(O)cc1.CC(CC(C)(CC(C)(C)c1ccc(O)cc1)c1ccc(O)cc1)c1ccc(O)cc1

nearest known ligand 0.38

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
SHBG P04278 1/20 0.38
NQO2 P16083 1/20 0.33
PTGS1 P23219 1/20 0.33
PTGS2 P35354 1/20 0.33
ESR1 P03372 4/20 0.32
ESR2 Q92731 4/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20414725 0.84 SHBG (0.47) SHBGNQO2PTGS1PTGS2ESR1
SCHEMBL18600 0.84 SHBG (0.53) SHBGNQO2PTGS1PTGS2ESR1
SCHEMBL247685 0.84 SHBG (0.53) SHBGNQO2PTGS1PTGS2ESR1
SCHEMBL18139 0.84 SHBG (0.53) SHBGPTGS1ESR1ESR2
SCHEMBL11245198 0.83 SHBG (0.35) SHBG
SCHEMBL6157069 0.81 SHBG (0.50) SHBGPTGS1ESR1ESR2
Phloroglucinol SCHEMBL28432567 0.80 SHBG (0.49) SHBGNQO2PTGS1PTGS2ESR1
SCHEMBL29113544 0.80 SHBG (0.41) SHBGPTGS1ESR1ESR2
SCHEMBL26035535 0.79 SHBG (0.47) SHBGNQO2PTGS1PTGS2ESR1
SCHEMBL9473539 0.79

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6855390-B1 Optical data carriers and method for producing the same BAYER AKTIENGESELLSCHAFT (DE) 2005-02-15 US disclosed
US-4328174-A DIMENSIONAL HEAT STABILITY BAYER AKTIENGESELLSCHAFT (DE) 1982-05-04 US disclosed