SCHEMBL26035535

SCHEMBL26035535

C/C(=C/C(C)(CC(C)(C)c1ccc(O)cc1)c1ccc(C)cc1)c1ccc(O)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SHBG P04278 1/20 0.47
PTGS1 P23219 4/20 0.39
PTGS2 P35354 3/20 0.39
NQO2 P16083 2/20 0.39
ESR2 Q92731 6/20 0.39
ESR1 P03372 5/20 0.39
ACHE P22303 2/20 0.37
MAPT P10636 4/20 0.37
RAB9A P51151 3/20 0.37
POLB P06746 1/20 0.37
MAOA P21397 1/20 0.37
MAOB P27338 1/20 0.37
NPC1 O15118 2/20 0.36
ESRRG P62508 3/20 0.34
LMNA P02545 2/20 0.34
CYP3A4 P08684 2/20 0.34
AR P10275 2/20 0.34
TSHR P16473 2/20 0.34
SLC6A2 P23975 2/20 0.34
SLC6A4 P31645 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18600 0.94 SHBG (0.53) SHBGPTGS1PTGS2NQO2ESR2
SCHEMBL247685 0.94 SHBG (0.53) SHBGPTGS1PTGS2NQO2ESR2
Phloroglucinol SCHEMBL28432567 0.90 SHBG (0.49) SHBGPTGS1PTGS2NQO2ESR2
SCHEMBL20414725 0.86 SHBG (0.47) SHBGPTGS1PTGS2NQO2ESR2
SCHEMBL6280436 0.79 SHBG (0.38) SHBGPTGS1PTGS2NQO2ESR2
SCHEMBL10631105 0.77 TAAR1 (0.40) SHBGESR2ESR1POLBESRRG
SCHEMBL10631111 0.77 TAAR1 (0.40) SHBGESR2ESR1POLBESRRG
SCHEMBL674805 0.73 ESR1 (0.44) PTGS1PTGS2ESR2ESR1MAPT
SCHEMBL674803 0.73 ESR1 (0.44) PTGS1PTGS2ESR2ESR1MAPT
SCHEMBL8021657 0.73 SHBG (0.35) SHBGPTGS1PTGS2NQO2ESR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3571240-B1 REDUCED COLOR POLYCARBONATE COMPOSITIONS, METHODS OF MANUFACTURE, AND ARTICLES THEREOF SABIC GLOBAL TECHNOLOGIES BV (NL) 2023-08-30 EP disclosed