SCHEMBL6280459

SCHEMBL6280459

CCNCCCOCCCNC(=O)NC

nearest known ligand 0.50

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.43
HSD17B10 Q99714 1/20 0.43
TSHR P16473 2/20 0.43
SAT1 P21673 1/20 0.41
EPHX2 P34913 6/20 0.40
KEAP1 Q14145 1/20 0.40
NFE2L2 Q16236 1/20 0.40
EPHX1 P07099 3/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6284129 0.88 MAPT (0.49) MAPTHSD17B10EPHX2EPHX1
SCHEMBL6287295 0.87 MAPT (0.44) MAPTHSD17B10TSHRSAT1EPHX2
SCHEMBL6287219 0.87 CYP2C19 (0.50) TSHRSAT1KEAP1NFE2L2EPHX1
SCHEMBL6290152 0.87 EPHX1 (0.50) TSHRKEAP1NFE2L2EPHX1
SCHEMBL6290247 0.86 EPHX1 (0.55) MAPTHSD17B10TSHREPHX2EPHX1
SCHEMBL6287625 0.85 KMT2A (0.40) MAPTHSD17B10TSHRSAT1EPHX2
SCHEMBL6290120 0.85 EPHX1 (0.54) KEAP1NFE2L2EPHX1
SCHEMBL6289721 0.84 KMT2A (0.43) MAPTHSD17B10SAT1EPHX2KEAP1
SCHEMBL6286750 0.83 KEAP1 (0.43) MAPTHSD17B10TSHREPHX2KEAP1
SCHEMBL6290323 0.81 KEAP1 (0.42) MAPTHSD17B10TSHREPHX2KEAP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6916854-B2 Heat and/or light curable films or coatings comprising polyurethanes or polyureaurethane copolymers having storage stability, used as automobile paints BASF AKTIENGESELLSCHAFT (DE) 2005-07-12 US disclosed
US-20040097642-A1 Unsaturated compounds containing carbamate terminal groups or urea terminal groups BASF AKTIENGESELLSCHAFT (DE) 2004-05-20 US disclosed