Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.46 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 6/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | KDM1A | O60341 | 3/20 | 0.41 |
| ▸ | SAT1 | P21673 | 3/20 | 0.41 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6290152 | 0.96 | EPHX1 (0.50) | CYP2C19MEN1KMT2AGLACYP1A2 | |
| SCHEMBL6290120 | 0.94 | EPHX1 (0.54) | CYP2C19MEN1KMT2AGLACYP1A2 | |
| SCHEMBL19150657 | 0.89 | CASP2 (0.42) | CYP2C19MEN1KMT2AGLACYP1A2 | |
| SCHEMBL6280459 | 0.87 | MAPT (0.43) | KEAP1NFE2L2EPHX1TSHRSAT1 | |
| SCHEMBL6289605 | 0.86 | KEAP1 (0.40) | CYP2C19MEN1KMT2AGLACYP1A2 | |
| SCHEMBL11382117 | 0.86 | KEAP1 (0.55) | CYP2C19MEN1KMT2AKEAP1NFE2L2 | |
| SCHEMBL6290110 | 0.85 | EPHX1 (0.57) | KEAP1NFE2L2EPHX1TSHRKDM1A | |
| SCHEMBL6283812 | 0.84 | CYP2C19 (0.52) | CYP2C19MEN1KMT2AGLACYP1A2 | |
| SCHEMBL13466509 | 0.81 | KEAP1 (0.61) | MEN1KMT2AKEAP1NFE2L2EPHX1 | |
| SCHEMBL6289669 | 0.81 | EPHX1 (0.63) | KEAP1NFE2L2EPHX1TSHRPAOX |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6916854-B2 | Heat and/or light curable films or coatings comprising polyurethanes or polyureaurethane copolymers having storage stability, used as automobile paints | BASF AKTIENGESELLSCHAFT (DE) | 2005-07-12 | — | — | US | disclosed |
| US-20040097642-A1 | Unsaturated compounds containing carbamate terminal groups or urea terminal groups | BASF AKTIENGESELLSCHAFT (DE) | 2004-05-20 | — | — | US | disclosed |