Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 7/20 | 0.36 |
| ▸ | RXRB | P28702 | 3/20 | 0.36 |
| ▸ | RXRG | P48443 | 2/20 | 0.36 |
| ▸ | PPARG | P37231 | 3/20 | 0.34 |
| ▸ | RARB | P10826 | 6/20 | 0.33 |
| ▸ | RARA | P10276 | 5/20 | 0.33 |
| ▸ | RARG | P13631 | 5/20 | 0.33 |
| ▸ | CYP26A1 | O43174 | 3/20 | 0.33 |
| ▸ | CYP26B1 | Q9NR63 | 3/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | CDC25A | P30304 | 1/20 | 0.32 |
| ▸ | CDC25B | P30305 | 1/20 | 0.32 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31650617 | 0.84 | RXRA (0.37) | RXRARXRBRXRGPPARGRARB | |
| SCHEMBL2061344 | 0.81 | KDM4E (0.45) | CYP3A4MALT1 | |
| SCHEMBL31650634 | 0.81 | KDM4E (0.45) | CYP3A4MALT1 | |
| SCHEMBL6280497 | 0.77 | PPARG (0.41) | PPARG | |
| SCHEMBL8771897 | 0.76 | CA12 (0.43) | RXRARXRBRXRGPPARGRARB | |
| SCHEMBL8563451 | 0.75 | RXRA (0.36) | RXRARXRBRXRGRARBRARA | |
| SCHEMBL30279114 | 0.74 | MALT1 (0.41) | CDC25ACDC25BMALT1 | |
| SCHEMBL445935 | 0.74 | MALT1 (0.41) | CDC25ACDC25BMALT1 | |
| SCHEMBL6992256 | 0.72 | ALDH1A1 (0.42) | PPARGCYP3A4HIF1AEPAS1 | |
| SCHEMBL8771731 | 0.72 | RXRA (0.34) | RXRARXRBRXRGRARBRARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6887896-B1 | 7-[(7-Alkoxy)-chrom-3-en-6-yl]-heptatrienoic acid and 7-[(3-alkoxy)-5,6-dihydronaphthalen-2-yl]-heptatrienoic acid derivatives having serum glucose reducing activity | ALLERGAN, INC. (US) | 2005-05-03 | — | — | US | disclosed |