Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARA | P10276 | 10/20 | 0.42 |
| ▸ | RARB | P10826 | 10/20 | 0.42 |
| ▸ | RXRA | P19793 | 10/20 | 0.42 |
| ▸ | RXRB | P28702 | 8/20 | 0.42 |
| ▸ | RXRG | P48443 | 8/20 | 0.42 |
| ▸ | PPARG | P37231 | 8/20 | 0.42 |
| ▸ | RARG | P13631 | 5/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | GALK1 | P51570 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.30 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6281276 | 1.00 | RARA (0.42) | RARARARBRXRARXRBRXRG | |
| SCHEMBL6279589 | 0.93 | RXRA (0.42) | RARARARBRXRARXRBRXRG | |
| SCHEMBL6279586 | 0.93 | RXRA (0.42) | RARARARBRXRARXRBRXRG | |
| SCHEMBL6275721 | 0.87 | PPARA (0.36) | RARARARBRXRAPPARGRARG | |
| SCHEMBL6275725 | 0.87 | PPARA (0.36) | RARARARBRXRAPPARGRARG | |
| SCHEMBL6281312 | 0.86 | RXRA (0.44) | RARARARBRXRARXRBRXRG | |
| SCHEMBL6284133 | 0.84 | RXRA (0.49) | RARARARBRXRARXRBRXRG | |
| SCHEMBL6284144 | 0.84 | RXRA (0.49) | RARARARBRXRARXRBRXRG | |
| SCHEMBL6277125 | 0.84 | PPARA (0.39) | RARARARBRXRARXRBRXRG | |
| SCHEMBL6277130 | 0.84 | PPARA (0.39) | RARARARBRXRARXRBRXRG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6887896-B1 | 7-[(7-Alkoxy)-chrom-3-en-6-yl]-heptatrienoic acid and 7-[(3-alkoxy)-5,6-dihydronaphthalen-2-yl]-heptatrienoic acid derivatives having serum glucose reducing activity | ALLERGAN, INC. (US) | 2005-05-03 | — | — | US | disclosed |