Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP2 | P42575 | 1/20 | 0.67 |
| ▸ | NAAA | Q02083 | 1/20 | 0.62 |
| ▸ | EPHX1 | P07099 | 8/20 | 0.61 |
| ▸ | FAAH | O00519 | 4/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.52 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16582460 | 1.00 | CASP2 (0.67) | CASP2NAAAEPHX1FAAHMEN1 | |
| SCHEMBL5543839 | 1.00 | CASP2 (0.67) | CASP2NAAAEPHX1FAAHMEN1 | |
| SCHEMBL14621023 | 1.00 | CASP2 (0.67) | CASP2NAAAEPHX1FAAHMEN1 | |
| SCHEMBL23567378 | 1.00 | CASP2 (0.67) | CASP2NAAAEPHX1FAAHMEN1 | |
| SCHEMBL6120008 | 1.00 | CASP2 (0.67) | CASP2NAAAEPHX1FAAHMEN1 | |
| SCHEMBL23567381 | 1.00 | CASP2 (0.67) | CASP2NAAAEPHX1FAAHMEN1 | |
| SCHEMBL5327335 | 1.00 | CASP2 (0.67) | CASP2NAAAEPHX1FAAHMEN1 | |
| SCHEMBL5331194 | 1.00 | CASP2 (0.67) | CASP2NAAAEPHX1FAAHMEN1 | |
| SCHEMBL462832 | 0.98 | CASP2 (0.63) | CASP2NAAAEPHX1FAAHMEN1 | |
| SCHEMBL3310816 | 0.91 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6969711-B2 | Cyclic diamine compounds and medicine containing the same | KOWA COMPANY, LTD. (JP) | 2005-11-29 | — | — | US | disclosed |
| EP-0987254-B1 | NOVEL CYCLIC DIAMINE COMPOUNDS AND MEDICINE CONTAINING THE SAME | KOWA CO (JP) | 2004-12-22 | — | — | EP | disclosed |
| US-20040038987-A1 | Novel cyclic diamine compounds and medicine containing the same | KOWA COMPANY, LTD. (JP) | 2004-02-26 | — | — | US | disclosed |
| CN-1118457-C | Cyclic diamine compounds and medicine contg. same | KOWA CO (JP) | 2003-08-20 | — | — | CN | disclosed |
| CN-1258283-A | Cyclic diamine compounds and medicine contg. same | KOWA CO (JP) | 2000-06-28 | — | — | CN | disclosed |
| EP-0987254-A1 | NOVEL CYCLIC DIAMINE COMPOUNDS AND MEDICINE CONTAINING THE SAME | Kowa Co., Ltd. (JP) | 2000-03-22 | — | — | EP | disclosed |
| US-4649218-A | ANTIDEPRESSANTS, ION SELECTIVE ELECTRODES, BATTERIES | YEDA RESEARCH AND DEVELOPMENT COMPANY LTD. (IL) | 1987-03-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040038987-A1 | Novel cyclic diamine compounds and medicine containing the same | LCAT, ACAT2, ACAT1 | CASP2 3426/4885NAAA 240/4885EPHX1 2367/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.