SCHEMBL6281871

SCHEMBL6281871

Nc1ccc(Oc2c(F)c(F)c(Oc3ccc(N)cc3C(F)(F)F)c(F)c2F)c(C(F)(F)F)c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 2/20 0.50
GAA P10253 2/20 0.50
TSHR P16473 2/20 0.50
GLA P06280 1/20 0.50
MAPT P10636 2/20 0.43
HSP90AA1 P07900 1/20 0.43
KDM4E B2RXH2 2/20 0.43
CRHBP P24387 1/20 0.43
CRHR2 Q13324 1/20 0.43
KIF11 P52732 3/20 0.40
AR P10275 3/20 0.35
MEN1 O00255 1/20 0.35
ALDH1A1 P00352 1/20 0.35
SRC P12931 1/20 0.35
HPGD P15428 1/20 0.35
CASP1 P29466 1/20 0.35
CASP7 P55210 1/20 0.35
KMT2A Q03164 1/20 0.35
ATM Q13315 1/20 0.35
NPSR1 Q6W5P4 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL142021 0.95 POLB (0.46) POLBGAATSHRGLAMAPT
SCHEMBL436804 0.87 GAA (0.59) POLBGAATSHRGLAMAPT
SCHEMBL29404322 0.87 GAA (0.59) POLBGAATSHRGLAMAPT
Hydrochloric Acid SCHEMBL8863493 0.85 GAA (0.57) POLBGAATSHRGLAMAPT
SCHEMBL27945658 0.83 GAA (0.47) POLBGAATSHRGLAMAPT
SCHEMBL30223697 0.82 GAA (0.50) POLBGAATSHRGLAKDM4E
SCHEMBL649657 0.81 TSHR (0.53) POLBGAATSHRGLAMAPT
SCHEMBL29352455 0.81 TSHR (0.53) POLBGAATSHRGLAMAPT
SCHEMBL22175023 0.81 GAA (0.53) POLBGAATSHRGLAMAPT
SCHEMBL29500406 0.81 GAA (0.53) POLBGAATSHRGLAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6891067-B2 Optical polyimide precursor, optical polyimide compound and fabricating method thereof SAMSUNG ELECTRONICS CO., LTD. (KR) 2005-05-10 US disclosed
US-20030065128-A1 Optical polyimide precursor, optical polyimide compound and fabricating method thereof YOU KYUNG-HEE (KR) 2003-04-03 US disclosed
US-6486292-B2 CORE, CLADDING STRUCTURE SAMSUNG ELECTRONICS CO., LTD. (KR) 2002-11-26 US disclosed
US-20010023286-A1 Optical polyimide precursor, optical polyimide compound and fabricating method thefeof SAMSUNG ELECTRONICS CO., LTD. (KR) 2001-09-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20010023286-A1 Optical polyimide precursor, optical polyimide compound and fabricating method thefeof POF1B, GTF2F1, MACF1 POLB 1436/4885GAA 3512/4885TSHR 799/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.