Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 7/20 | 0.38 |
| ▸ | DPP7 | Q9UHL4 | 5/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.38 |
| ▸ | FYN | P06241 | 3/20 | 0.37 |
| ▸ | DPP8 | Q6V1X1 | 3/20 | 0.36 |
| ▸ | DPP9 | Q86TI2 | 3/20 | 0.36 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.34 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.34 |
| ▸ | FEN1 | P39748 | 2/20 | 0.34 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.34 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.34 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.34 |
| ▸ | AHR | P35869 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL628259 | 1.00 | DPP4 (0.38) | DPP4DPP7KCNH2FYNDPP8 | |
| SCHEMBL628258 | 0.90 | DPP4 (0.38) | DPP4DPP7KCNH2FYNDPP8 | |
| SCHEMBL627456 | 0.87 | FYN (0.48) | DPP4DPP7KCNH2FYNPIK3CA | |
| SCHEMBL627458 | 0.87 | FYN (0.48) | DPP4DPP7KCNH2FYNPIK3CA | |
| SCHEMBL627457 | 0.84 | DPP4 (0.40) | DPP4DPP7KCNH2FYNDPP8 | |
| SCHEMBL627466 | 0.83 | HASPIN (0.43) | FYNPIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL627468 | 0.83 | HASPIN (0.43) | FYNPIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL627321 | 0.82 | FYN (0.48) | KCNH2FYNPIK3CDPIK3CAPIK3CB | |
| SCHEMBL627323 | 0.82 | FYN (0.48) | KCNH2FYNPIK3CDPIK3CAPIK3CB | |
| SCHEMBL626796 | 0.81 | PIK3CA (0.39) | FYNPIK3CDPIK3CAPIK3C3PIK3CB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012020215-A1 | AMINO- IMIDAZOLOTHIADIAZOLES FOR USE AS PROTEIN OR LIPID KINASE INHIBITORS | CENTRO NACIONAL DE INVESTIGACIONES ONCOLÓGICAS (CNIO) (ES) | 2012-02-16 | — | — | WO | disclosed |