Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX12 | P18054 | 1/20 | 0.66 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.59 |
| ▸ | RAB9A | P51151 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 6/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | G6PD | P11413 | 1/20 | 0.46 |
| ▸ | PSD | A5PKW4 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24110995 | 0.81 | ALOX12 (0.57) | ALOX12MDM2RAB9AMAPTPDE7A | |
| SCHEMBL12115517 | 0.80 | ALOX12 (0.71) | ALOX12MDM2RAB9AMAPTSMN1; SMN2 | |
| SCHEMBL30454788 | 0.80 | ALOX12 (1.00) | ALOX12MDM2RAB9AMAPTALDH1A1 | |
| SCHEMBL6281843 | 0.79 | SMN1; SMN2 (0.57) | RAB9AMAPTKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL6280169 | 0.79 | KDM4E (0.57) | RAB9AMAPTKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL6286175 | 0.78 | SMN1; SMN2 (0.70) | RAB9AMAPTKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL6281164 | 0.78 | SMN1; SMN2 (0.60) | RAB9AMAPTKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL24089986 | 0.78 | ALOX12 (0.55) | ALOX12MDM2RAB9AMAPTSMN1; SMN2 | |
| SCHEMBL6279307 | 0.78 | KDM4E (0.56) | RAB9AMAPTKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL6278493 | 0.76 | SMN1; SMN2 (0.70) | RAB9AMAPTKDM4EALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6897213-B1 | Heterocycles as cholecystokinin (CCK) ligands | WARNER-LAMBERT COMPANY (US) | 2005-05-24 | — | — | US | disclosed |
| WO-1996020178-A1 | NOVEL HETEROCYCLES AS CHOLECYSTOKININ (CCK) LIGANDS | WARNER-LAMBERT COMPANY (US) | 1996-07-04 | — | — | WO | disclosed |