Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.70 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.70 |
| ▸ | MAPT | P10636 | 2/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.57 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6281164 | 0.86 | SMN1; SMN2 (0.60) | SMN1; SMN2KDM4EMAPTALDH1A1NPSR1 | |
| SCHEMBL6276607 | 0.85 | ALDH1A1 (0.65) | SMN1; SMN2KDM4EMAPTALDH1A1NPSR1 | |
| SCHEMBL6278052 | 0.82 | MAPT (0.76) | SMN1; SMN2KDM4EMAPTALDH1A1RAB9A | |
| SCHEMBL29175098 | 0.81 | SMN1; SMN2 (0.66) | SMN1; SMN2KDM4EALDH1A1NPSR1RAB9A | |
| SCHEMBL2631381 | 0.81 | MAPK1 (0.74) | SMN1; SMN2ALDH1A1NPSR1RAB9ATP53 | |
| SCHEMBL6285402 | 0.80 | MAPT (0.56) | SMN1; SMN2KDM4EMAPTALDH1A1RAB9A | |
| SCHEMBL6279765 | 0.80 | MAPT (0.60) | SMN1; SMN2KDM4EMAPTALDH1A1NPSR1 | |
| SCHEMBL6281843 | 0.78 | SMN1; SMN2 (0.57) | SMN1; SMN2KDM4EMAPTALDH1A1RAB9A | |
| SCHEMBL6282785 | 0.78 | ALOX12 (0.66) | SMN1; SMN2KDM4EMAPTALDH1A1RAB9A | |
| SCHEMBL6280169 | 0.78 | KDM4E (0.57) | SMN1; SMN2KDM4EMAPTALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6897213-B1 | Heterocycles as cholecystokinin (CCK) ligands | WARNER-LAMBERT COMPANY (US) | 2005-05-24 | — | — | US | disclosed |