Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | PGR | P06401 | 4/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6279895 | 0.69 | PGR (0.43) | PGR | |
| SCHEMBL6283928 | 0.69 | GRM2 (0.35) | PGR | |
| SCHEMBL4910089 | 0.65 | PGR (0.47) | PGR | |
| SCHEMBL4913276 | 0.65 | PGR (0.64) | PGR | |
| SCHEMBL25429798 | 0.65 | FABP6 (0.38) | LMNA | |
| SCHEMBL4172079 | 0.65 | PARP10 (0.38) | LMNA | |
| SCHEMBL11436661 | 0.65 | GAA (0.50) | LMNA | |
| SCHEMBL20804966 | 0.65 | AHR (0.40) | — | |
| SCHEMBL3003659 | 0.64 | ALOX15 (0.41) | — | |
| SCHEMBL78394 | 0.63 | PGR (0.61) | PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005095366-A1 | 7-ARYL 1,5-DIHYDRO-4,1-BENZOXAZEPIN-2(3H)-ONE DERIVATIVES AND THEIR USE AS PROGESTERONE RECEPTOR MODULATORS | WYETH (US) | 2005-10-13 | — | — | WO | disclosed |