Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | PGR | P06401 | 2/20 | 0.32 |
| ▸ | OTUD7B | Q6GQQ9 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4901931 | 0.77 | PGR (0.43) | PGR | |
| SCHEMBL6279895 | 0.73 | PGR (0.43) | PGROTUD7B | |
| SCHEMBL6282794 | 0.69 | LMNA (0.34) | PGR | |
| SCHEMBL11436661 | 0.66 | GAA (0.50) | — | |
| SCHEMBL28349524 | 0.65 | ALDH1A1 (0.42) | — | |
| SCHEMBL7481521 | 0.64 | PGR (0.57) | PGR | |
| SCHEMBL25429798 | 0.63 | FABP6 (0.38) | — | |
| SCHEMBL20804966 | 0.63 | AHR (0.40) | — | |
| SCHEMBL28350046 | 0.63 | KDM4E (0.41) | GRM2 | |
| SCHEMBL28882198 | 0.63 | ALDH1A1 (0.57) | GRM2BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005095366-A1 | 7-ARYL 1,5-DIHYDRO-4,1-BENZOXAZEPIN-2(3H)-ONE DERIVATIVES AND THEIR USE AS PROGESTERONE RECEPTOR MODULATORS | WYETH (US) | 2005-10-13 | — | — | WO | disclosed |