SCHEMBL6282969

SCHEMBL6282969

CC1(C)C(=O)N(C(=O)c2cccc3ccccc23)C(=O)N1Cc1ccc(Cl)cc1

nearest known ligand 0.49

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 5/20 0.49
FFAR2 O15552 1/20 0.48
DRD4 P21917 1/20 0.43
MEN1 O00255 2/20 0.42
KMT2A Q03164 2/20 0.42
TACR1 P25103 1/20 0.42
ALDH1A1 P00352 1/20 0.42
HSP90AA1 P07900 1/20 0.42
MAPT P10636 1/20 0.42
HPGD P15428 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
BCHE P06276 1/20 0.40
CBX7 O95931 1/20 0.39
CDY1; CDY1B Q9Y6F8 1/20 0.39
C5AR1 P21730 1/20 0.39
FNTA P49354 1/20 0.38
FNTB P49356 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6285484 0.90 FNTA (0.47) CNR2FFAR2DRD4MEN1KMT2A
SCHEMBL6285114 0.87 FNTA (0.47) CNR2FFAR2MEN1KMT2ATACR1
SCHEMBL6278686 0.81 BCHE (0.43) MEN1KMT2ATACR1BCHECBX7
SCHEMBL6282978 0.80 DRD4 (0.43) DRD4MEN1KMT2AALDH1A1HPGD
SCHEMBL6285219 0.79 FNTA (0.50) FFAR2DRD4MEN1KMT2ATACR1
SCHEMBL6284085 0.78 BCHE (0.49) CNR2ALDH1A1MAPTBCHECBX7
SCHEMBL6285454 0.78 CNR2 (0.45) CNR2FFAR2MEN1KMT2ATACR1
SCHEMBL6283110 0.77 AVPR1A (0.44) CNR2DRD4MEN1KMT2ATACR1
SCHEMBL6285675 0.76 CBX7 (0.40) CNR2MEN1KMT2AALDH1A1HSP90AA1
SCHEMBL6284006 0.74 ALDH1A1 (0.45) CNR2MEN1KMT2AALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6919365-B2 Imidazolidinedione derivatives and use thereof as drugs SENJU PHARMACEUTICAL CO., LTD. (JP) 2005-07-19 US disclosed
US-20040110811-A1 Novel imidazolidinedione derivatives and use thereof as drugs SENJU PHARMACEUTICAL CO., LTD. (JP) 2004-06-10 US disclosed
EP-1384715-A1 NOVEL IMIDAZOLIDINEDIONE DERIVATIVES AND USE THEREOF AS DRUGS Senju Pharmaceutical Co., Ltd. (JP) 2004-01-28 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040110811-A1 Novel imidazolidinedione derivatives and use thereof as drugs CMA1, TPSD1, TPSB2 CNR2 650/4885FFAR2 2361/4885DRD4 182/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.