Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLD1 | Q13393 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | HTR1A | P08908 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
| ▸ | HTR2C | P28335 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | SORD | Q00796 | 1/20 | 0.44 |
| ▸ | SLC6A7 | Q99884 | 1/20 | 0.43 |
| ▸ | KARS1 | Q15046 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.41 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8040 | 0.90 | PLD1 (0.56) | PLD1KDM4EMEN1ALDH1A1CYP1A2 | |
| SCHEMBL29403876 | 0.90 | PLD1 (0.56) | PLD1KDM4EMEN1ALDH1A1CYP1A2 | |
| SCHEMBL1477436 | 0.90 | PLD1 (0.56) | PLD1KDM4EMEN1ALDH1A1CYP1A2 | |
| Hydrochloric Acid SCHEMBL25306600 | 0.88 | PLD1 (0.55) | PLD1KDM4EMEN1ALDH1A1CYP1A2 | |
| Hydrochloric Acid SCHEMBL2956941 | 0.88 | PLD1 (0.55) | PLD1KDM4EMEN1ALDH1A1CYP1A2 | |
| Fumaric Acid SCHEMBL27619906 | 0.86 | KDM4E (0.51) | PLD1KDM4EMEN1ALDH1A1CYP1A2 | |
| Acetic Acid SCHEMBL27600556 | 0.86 | KDM4E (0.52) | PLD1KDM4EMEN1ALDH1A1CYP1A2 | |
| SCHEMBL30306065 | 0.83 | CHRNB2 (0.55) | PLD1KDM4EMEN1ALDH1A1CYP1A2 | |
| SCHEMBL25378983 | 0.83 | CHRNB2 (0.55) | PLD1KDM4EMEN1ALDH1A1CYP1A2 | |
| Piperidine SCHEMBL1270139 | 0.83 | PLD1 (0.50) | PLD1KDM4EMEN1ALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6894050-B2 | 5-HT receptor ligands and uses thereof | PFIZER INC. (US) | 2005-05-17 | — | — | US | disclosed |
| US-20050090503-A1 | 5-HT receptor ligands and uses thereof | PFIZER INC | 2005-04-28 | — | — | US | disclosed |
| US-20050020604-A1 | 5-HT receptor ligands and uses thereof | PFIZER INC | 2005-01-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050090503-A1 | 5-HT receptor ligands and uses thereof | HTR2A, HTR1A, HTR5A | PLD1 1606/4885KDM4E 4327/4885MEN1 3388/4885 |
| US-20050020604-A1 | 5-HT receptor ligands and uses thereof | HTR2A, HTR1A, HTR5A | PLD1 1606/4885KDM4E 4327/4885MEN1 3388/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.