SCHEMBL6283095

SCHEMBL6283095

CC1(C)C(=O)N(C(=O)c2cccc3ccccc23)C(=O)N1CC(=O)c1ccccc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CBX7 O95931 3/20 0.42
CDY1; CDY1B Q9Y6F8 3/20 0.42
BCHE P06276 1/20 0.41
CDYL Q9Y232 3/20 0.40
AVPR1A P37288 1/20 0.38
NR4A1 P22736 1/20 0.38
NR4A2 P43354 1/20 0.38
NR4A3 Q92570 1/20 0.38
PTPN1 P18031 1/20 0.38
ALDH1A1 P00352 4/20 0.37
KDM4E B2RXH2 3/20 0.37
MAPT P10636 3/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
CNR2 P34972 1/20 0.37
ELANE P08246 1/20 0.37
LMNA P02545 3/20 0.37
MEN1 O00255 2/20 0.37
GMNN O75496 2/20 0.37
POLB P06746 2/20 0.37
HPGD P15428 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6285675 0.92 CBX7 (0.40) CBX7CDY1; CDY1BBCHECDYLPTPN1
SCHEMBL6284006 0.90 ALDH1A1 (0.45) ALDH1A1KDM4EMAPTCNR2ELANE
SCHEMBL6278686 0.90 BCHE (0.43) CBX7CDY1; CDY1BBCHECDYLAVPR1A
SCHEMBL6285241 0.88 CBX7 (0.40) CBX7CDY1; CDY1BBCHECDYLAVPR1A
SCHEMBL6287758 0.85 BCHE (0.40) CBX7CDY1; CDY1BBCHECDYLAVPR1A
SCHEMBL6283097 0.81 CBX7 (0.42) CBX7CDY1; CDY1BBCHECDYLPTPN1
SCHEMBL6284085 0.79 BCHE (0.49) CBX7CDY1; CDY1BBCHECDYLAVPR1A
SCHEMBL6282969 0.79 CNR2 (0.49) CBX7CDY1; CDY1BBCHEALDH1A1MAPT
SCHEMBL6282910 0.77 BCHE (0.41) CBX7CDY1; CDY1BBCHECDYLAVPR1A
SCHEMBL6285484 0.76 FNTA (0.47) ALDH1A1MAPTCNR2LMNAMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6919365-B2 Imidazolidinedione derivatives and use thereof as drugs SENJU PHARMACEUTICAL CO., LTD. (JP) 2005-07-19 US disclosed
US-20040110811-A1 Novel imidazolidinedione derivatives and use thereof as drugs SENJU PHARMACEUTICAL CO., LTD. (JP) 2004-06-10 US disclosed
EP-1384715-A1 NOVEL IMIDAZOLIDINEDIONE DERIVATIVES AND USE THEREOF AS DRUGS Senju Pharmaceutical Co., Ltd. (JP) 2004-01-28 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040110811-A1 Novel imidazolidinedione derivatives and use thereof as drugs CMA1, TPSD1, TPSB2 CBX7 2579/4885CDY1; CDY1B 2124/4885BCHE 515/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.