Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | ALPL | P05186 | 1/20 | 0.41 |
| ▸ | ALPI | P09923 | 1/20 | 0.41 |
| ▸ | ALPG | P10696 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.39 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | GHSR | Q92847 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | PTPRB | P23467 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5221235 | 0.79 | KDM4E (0.49) | MAPTKDM4EMEN1KMT2ANPC1 | |
| SCHEMBL6276844 | 0.77 | MAPT (0.42) | MAPTKDM4EMEN1KMT2ANPC1 | |
| SCHEMBL13690849 | 0.74 | PPARA (0.53) | MAPTKDM4EMEN1KMT2ANPC1 | |
| SCHEMBL12376667 | 0.73 | MAPT (0.55) | MAPTKDM4EMEN1KMT2ANPC1 | |
| SCHEMBL3511351 | 0.72 | KDM4E (0.46) | MAPTKDM4EMEN1KMT2ANPC1 | |
| SCHEMBL5391748 | 0.72 | ALDH1A1 (0.49) | MAPTKDM4EMEN1KMT2APOLB | |
| SCHEMBL1691754 | 0.72 | KDM4E (0.53) | KDM4EKMT2APOLBALDH1A1SMN1; SMN2 | |
| SCHEMBL1691112 | 0.71 | PTPRB (0.52) | KDM4EMEN1KMT2ANPC1RAB9A | |
| SCHEMBL6279972 | 0.71 | — | — | |
| SCHEMBL6281120 | 0.71 | TSHR (0.31) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6841703-B2 | Open chain alkoxyamine compounds and their use as polymerization regulators | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2005-01-11 | — | — | US | disclosed |
| EP-1100772-B1 | OPEN CHAIN ALKOXYAMINE COMPOUNDS AND THEIR USE AS POLYMERIZATION REGULATORS | CIBA SC HOLDING AG (CH) | 2004-04-14 | — | — | EP | disclosed |
| US-20030125489-A1 | Open chain alkoxyamine compounds and their use as polymerization regulators | NESVADBA PETER (CH) | 2003-07-03 | — | — | US | disclosed |
| US-6518326-B1 | Open chain alkoxyamine compounds and their use as polymerization regulators | CIBA SPECIALTY CHEMICALS CORPORATION | 2003-02-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030125489-A1 | Open chain alkoxyamine compounds and their use as polymerization regulators | ALOX5, PTGER1, ALOX12 | MAPT 3566/4885KDM4E 1073/4885MEN1 4480/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.