Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | NOS2 | P35228 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | DPP4 | P27487 | 2/20 | 0.39 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.39 |
| ▸ | MIF | P14174 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL306112 | 1.00 | TSHR (0.52) | TSHRTAAR1ADRA2AADRA2CCYP2D6 | |
| SCHEMBL304645 | 1.00 | TSHR (0.52) | TSHRTAAR1ADRA2AADRA2CCYP2D6 | |
| SCHEMBL893216 | 0.83 | TSHR (0.52) | TSHRTAAR1ADRA2AADRA2CCYP2D6 | |
| SCHEMBL6283476 | 0.82 | TSHR (0.65) | TSHRTAAR1CYP2D6LMNADPP4 | |
| SCHEMBL9750479 | 0.81 | TSHR (0.50) | TSHRTAAR1ADRA2AADRA2CCYP2D6 | |
| SCHEMBL3280292 | 0.79 | ADRA2A (0.54) | TSHRTAAR1ADRA2AADRA2CCYP2D6 | |
| SCHEMBL4778223 | 0.79 | LMNA (0.48) | TSHRADRA2AADRA2CCYP2D6LMNA | |
| SCHEMBL11887151 | 0.79 | ADRA2A (0.54) | TSHRTAAR1ADRA2AADRA2CCYP2D6 | |
| Acetone SCHEMBL28777513 | 0.79 | CYP2D6 (0.43) | TSHRCYP2D6LMNAALDH1A1 | |
| SCHEMBL2240790 | 0.78 | TSHR (0.52) | TSHRTAAR1ADRA2AADRA2CCYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020145347-A1 | PRODUCTION METHOD FOR α-CHLOROETHYL BENZYL CHLORIDE AND PRODUCTION METHOD FOR CHLOROMETHYLSTYRENE | 長瀬産業株式会社 | 2020-07-16 | — | — | WO | claimed |
| WO-2020145347-A1 | PRODUCTION METHOD FOR α-CHLOROETHYL BENZYL CHLORIDE AND PRODUCTION METHOD FOR CHLOROMETHYLSTYRENE | 長瀬産業株式会社 | 2020-07-16 | — | — | WO | disclosed |
| CN-104045626-B | Compounds based on 4-phenyl-6-(2,2,2-trifluoro-1-phenyl ethoxy) pyrimidine and application method thereof | 莱西肯医药有限公司 | 2017-01-11 | — | — | CN | disclosed |
| EP-1978411-B1 | Toner preparation method and apparatus, and toner prepared thereby | RICOH CO LTD (JP) | 2015-12-23 | — | — | EP | disclosed |
| EP-1992993-B1 | Method and apparatus for manufacturing toner, and electrophotographic toner manufactured by the method | RICOH CO LTD (JP) | 2015-12-09 | — | — | EP | disclosed |
| CN-104045626-A | Compounds based on 4-phenyl-6-(2,2,2-trifluoro-1-phenyl ethoxy) pyrimidine and application method thereof | LEXICON PHARMACEUTICALS INC | 2014-09-17 | — | — | CN | disclosed |
| CN-101591332-B | compounds based on 4-phenyl-6- (2,2, 2-trifluoro-1-phenylethoxy) pyrimidine and methods of use thereof | LEXICON PHARMACEUTICALS INC | 2014-04-16 | — | — | CN | disclosed |
| CN-101284817-B | Methods of preparing imidazole-based compounds | LEXICON PHARMACEUTICALS INC | 2013-06-26 | — | — | CN | disclosed |
| US-20120202912-A1 | SURFACE TREATMENT BY PHOTOPOLYMERISATION TO OBTAIN BIOCIDAL PROPERTIES | DESARROLLO DEL GRAFTING S.L. (ES) | 2012-08-09 | — | — | US | disclosed |
| US-8137087-B2 | Dripping and discharging droplets of toner constituent liquid, solidifying and granulating; dripper comprises thin film with nozzles, and oscillator, and oscillation amplifier; improved fluidity and chargeability | RICOH COMPANY, LTD. (JP) | 2012-03-20 | — | — | US | disclosed |
| US-6858374-B2 | Lithographic printing plate precursor | FUJI PHOTO FILM CO., LTD. (JP) | 2005-02-22 | — | — | US | disclosed |
| US-20030068575-A1 | Lithographic printing plate precursor | FUJI PHOTO FILM CO., LTD. | 2003-04-10 | — | — | US | disclosed |
| JP-2001072619-A | INDUSTRIAL PRODUCTION OF CHLOROMETHYLSTYRENES | NIPPON LIGHT METAL CO LTD | 2001-03-21 | — | — | JP | disclosed |
| JP-2001072622-A | PRODUCTION OF CHLOROMETHYLSTYRENES | NIPPON LIGHT METAL CO LTD | 2001-03-21 | — | — | JP | disclosed |
| JP-2001072621-A | PRODUCTION OF CHLOROMETHYLSTYRENES | NIPPON LIGHT METAL CO LTD | 2001-03-21 | — | — | JP | disclosed |
| EP-0368279-B1 | Silane coupling agent and glass fiber product for laminates | NITTO BOSEKI CO LTD (JP) | 2000-03-15 | — | — | EP | disclosed |
| US-5149839-A | Improved impregnation, solvent resistance, heat resistance and low water absoprtion properties | NITTO BOSEKI CO., LTD. (JP) | 1992-09-22 | — | — | US | disclosed |
| US-5069971-A | With epoxy resins, printed circuits, diaminoalklyalkoxysilane | NITTO BOSEKI CO., LTD. (JP) | 1991-12-03 | — | — | US | disclosed |
| EP-0368279-A1 | Silane coupling agent and glass fiber product for laminates | NITTO BOSEKI CO., LTD. (JP) | 1990-05-16 | — | — | EP | disclosed |
| US-3962357-A | FROM SUBSTITUTED ETHYLTOLUENE, CONTINUOUS, SINGLE STEP | ROHM AND HAAS COMPANY (US) | 1976-06-08 | — | — | US | disclosed |